Chen LJ

No ORCID on file · 3 papers in corpus · active 2021-2022

Study types

  • article 2

Condition tags

  • endometriosis 2
  • infertility 2
2022
Magnetic-activated cell sorting of nonapoptotic spermatozoa with a high DNA fragmentation index improves the live birth rate and decreases transfer cycles of IVF/ICSI.
Asian journal of andrology ·doi:10.4103/aja202161

The present study aimed to evaluate the clinical outcomes of magnetic-activated cell sorting (MACS) in sperm preparation for male subjects with a sperm DNA fragmentation index (DFI) ≥30%. A total of 86 patients who had undergone their first…

article 2021
BAG2-Mediated Inhibition of CHIP Expression and Overexpression of MDM2 Contribute to the Initiation of Endometriosis by Modulating Estrogen Receptor Status
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2020.554190

Endometriosis is an estrogen-dependent gynecological disease primarily affecting women of childbearing age, which gives rise to pelvic pain calling for multiple operations, and sometimes leading to infertility. However, the etiology of endo…

article 2021
Repression of FBXW7 by HES5 contributes to inactivation of the TGF‐β signaling pathway and alleviation of endometriosis
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202000438rrr

Endometriosis (EMS) is a gynecologic disorder associated with infertility and characterized by the endometrial-type mucosa outside the uterine cavity. Currently available treatment modalities are limited to undesirable effects. Thus, in the…