BACKGROUND: Postmenopausal women are at elevated risk for carotid atherosclerosis due to estrogen decline, yet existing prediction models do not incorporate genetic markers. This study aimed to develop and validate a risk prediction model c…
OBJECTIVE: This study aims to demonstrate that the EN2 protein in cervical mucus may serve as a novel biomarker for screening endometrial cancer. MATERIALS AND METHODS: This study included 133 patients who were treated at Beijing Obstetric…
BACKGROUND: Alarelin acetate, a synthetic gonadotropin-releasing hormone (GnRH) analogue, is widely used to manage endometriosis and hormone-sensitive malignancies. Although its safety profile is generally favorable, we report the first doc…
BACKGROUND: Hereditary primary hyperparathyroidism (PHPT) accounts for 5-10% of all PHPT cases, necessitating genetic testing for diagnosis and management. Among these, hyperparathyroidism-jaw tumor syndrome (HPT-JT) is an autosomal dominan…
Per- and polyfluoroalkyl substances (PFASs) are a class of anthropogenic organic compounds widely present in the natural and human living environments. These emerging persistent pollutants can enter the human body through multiple channels,…
BACKGROUND AND OBJECTIVE: Cancer is an important disease and can occur anywhere in the body. It is caused by uncontrolled cell growth that spreads to other body parts. This study extensively investigated the transmembrane receptor tissue fa…
Tissue factor (TF) has been confirmed to be specifically expressed by vascular endothelial cells (VECs) in solid tumors and certain types of malignant tumor cells. Coagulation factor VII (FVII) can specifically bind to TF with high affinity…
The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is one of the bioactive substances contributing to its medical…
PURPOSE: Mucin-1(MUC1), a type of glucoprotein, has various expression statuses on the endometrium at different menstrual phases. Normal expression of MCU1 is closely related to successful blastocyst implantation. MUC1 was synthesized and s…
Although smokers have increased susceptibility and severity of seasonal influenza virus infection, there is no report about the risk of 2009 pandemic H1N1 (pdmH1N1) or avian H9N2 (H9N2/G1) virus infection in smokers. In our study, we used m…
Adenomyosis is a finding that is associated with dysmenorrhea and heavy menstrual bleeding, associated with PI3K/AKT signaling overactivity. To investigate the effect of metformin on the growth of eutopic endometrial stromal cells (ESCs) fr…
Objective To detect the expressions of mucin-1 and tumor necrosis factor receptor-I(TNFR-I) in endometriosis(EMs) endometrium,and investigate the relationship between the regulation of serum TNF-α and EMs-related infertility.Methods The end…
cases of patients with endometriosis were investigated to probe the relations of three TCM syndrome types to the indexes of B-ultrasonic image.Basing on the inner relations,the author sets forth a primary view on the imaging basis of TCM sy…