Veldhuis JD

No ORCID on file · 2 papers in corpus · active 2018-2019
2019
Determining the Relationship Between Hot Flushes and LH Pulses in Menopausal Women Using Mathematical Modeling.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2018-02797

BackgroundHypothalamic kisspeptin/neurokinin B/dynorphin (KNDy) neurones regulate LH pulsatility. It is widely accepted that the menopausal hot flush (HF) consistently synchronizes with the LH pulse, implicating the hypothalamic KNDy neuron…

2018
Neurokinin B Regulates Gonadotropin Secretion, Ovarian Follicle Growth, and the Timing of Ovulation in Healthy Women.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2017-01306

ContextNeurokinin B (NKB) is obligate for human puberty, but its role in adult female gonadotropin secretion and ovarian follicle growth is unknown.ObjectiveTo investigate antagonism of NKB on pulsatile gonadotropin-releasing hormone (GnRH)…