Channa Jayasena

ORCID: 0000-0002-2578-8223 · 4 papers in corpus
preprint 2025
Temporal trends in endometriosis incidence, prevalence and symptom burden in England 2010-2020: A population-based cohort study
·doi:10.2139/ssrn.5472941
2019
Determining the Relationship Between Hot Flushes and LH Pulses in Menopausal Women Using Mathematical Modeling.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2018-02797

BackgroundHypothalamic kisspeptin/neurokinin B/dynorphin (KNDy) neurones regulate LH pulsatility. It is widely accepted that the menopausal hot flush (HF) consistently synchronizes with the LH pulse, implicating the hypothalamic KNDy neuron…

2015
Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2015-2332

ContextIn vitro fertilization (IVF) treatment is an effective therapy for infertility, but can result in the potentially life-threatening complication, ovarian hyperstimulation syndrome (OHSS).ObjectiveThis study aimed to investigate whethe…

2014
Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization.
The Journal of clinical investigation ·doi:10.1172/jci75730

BackgroundPatients with mutations that inactivate kisspeptin signaling are infertile. Kisspeptin-54, the major circulating isoform of kisspeptin in humans, potently stimulates reproductive hormone secretion in humans. Animal studies suggest…