Channa Jayasena

ORCID: 0000-0002-2578-8223 · 4 papers in corpus
2025
Temporal trends in endometriosis incidence, prevalence and symptom burden in England 2010-2020: A population-based cohort study
·doi:10.2139/ssrn.5472941
observational 2019
Determining the Relationship Between Hot Flushes and LH Pulses in Menopausal Women Using Mathematical Modeling
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2018-02797

BACKGROUND: Hypothalamic kisspeptin/neurokinin B/dynorphin (KNDy) neurones regulate LH pulsatility. It is widely accepted that the menopausal hot flush (HF) consistently synchronizes with the LH pulse, implicating the hypothalamic KNDy neur…

rct 2015
Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2015-2332

CONTEXT: In vitro fertilization (IVF) treatment is an effective therapy for infertility, but can result in the potentially life-threatening complication, ovarian hyperstimulation syndrome (OHSS). OBJECTIVE: This study aimed to investigate …

nonrandomized-trial 2014
Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization
The Journal of clinical investigation ·doi:10.1172/jci75730

BACKGROUND: Patients with mutations that inactivate kisspeptin signaling are infertile. Kisspeptin-54, the major circulating isoform of kisspeptin in humans, potently stimulates reproductive hormone secretion in humans. Animal studies sugge…