Renato Polimanti

Endometriosis is a chronic systemic disease affecting ~10% of women, yet its genetic basis and molecular mechanisms remain poorly understood. Hence, here we conducted a genome-wide association study of endometriosis and adenomyosis in ~1.4 …

Endometriosis is a chronic systemic disease affecting ~10%women, yet its geneticbasis and molecular mechanisms remain poorlyunderstood. Hence, we conducted a genome-wide association study of endometriosis and adenomyosis in ~1.4 million wom…

We conducted a multi-ancestry genome-wide association study of endometriosis and adenomyosis in almost 1.4 million women, including 105,869 cases, aiming to expand endometriosis loci discovery across ancestries, dissect symptom-specific eff…

IMPORTANCE: Although psychological traumas have been associated with endometriosis, limited information is available regarding the role of trauma type and genetic predisposition. OBJECTIVE: To examine the relationship between traumatic exp…

Individuals suffering from chronic pain develop substance use disorders (SUDs) more often than others. Understanding the shared genetic influences underlying the comorbidity between chronic pain and SUDs will lead to a greater understanding…

ABSTRACT Endometriosis is a chronic gynecologic disease that causes pelvic pain and is often seen in association with depression and anxiety. The association with these mental health conditions was previously linked to chronic pain, althoug…

IMPORTANCE: Endometriosis is a common chronic gynecologic pathology with a large negative impact on women's health. Beyond severe physical symptoms, endometriosis is also associated with several psychiatric comorbidities, including depressi…