Jiao Fan

No ORCID on file · 3 papers in corpus · active 2023-2025

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 2
  • infertility 1
  • adenomyosis 1
other 2025
Hypermethylation of Klotho and Peroxisome Proliferator-Activated Receptor γ Concomitant with Overexpression of DNA Methyltransferase 1 in Adenomyosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-024-01599-4

Cellular senescence is known to be involved in tissue repair, but its role in adenomyosis remains unclear. This study was tasked to evaluate the expression of Klotho, a well-known aging-suppressing protein, as well as PPARγ and DNMT1 in ade…

article 2025
Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway
Molecular medicine reports ·doi:10.3892/mmr.2025.13722

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome prolif…

article 2023
A cohort study on IVF outcomes in infertile endometriosis patients: the effects of rapamycin treatment
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2023.103319

RESEARCH QUESTION: Can rapamycin, used as an anti-senescence drug before IVF cycles, improve the IVF outcomes of women with endometriosis by reducing oxidative stress and senescence? DESIGN: This retrospective analysis involved 168 endomet…