Wu H

The purpose of this study was to investigate the anti-inflammatory effects of Perilla Seed Extract (PSE) and its active ingredient on Inflammatory Bowel Disease (IBD) in vitro and in vivo. Thirty-two C57/BL mice were randomly divided into f…

PURPOSE: As microwave ablation (MWA) becomes an increasingly popular treatment for gynecological diseases, complications such as surgical site infections (SSIs) have emerged as critical concerns, particularly in high-risk patient population…

Both T cell-mediated rejection (TCMR) and BK polyomavirus-associated nephropathy (BKPyVAN) pose significant obstacles to successful kidney transplantation, emphasizing the importance of their accurate diagnosis for prompt medical interventi…

Suicide is a complex behavior strongly associated with depression. Despite extensive research, an objective biomarker for evaluating suicide risk precisely and timely is still lacking. Using the precision resting-state fMRI method, we studi…

BACKGROUND: Infertility is a public health issue closely related to obesity. However, the relationship between obesity-related indicators and infertility is currently uncertain. The present study aimed to explore the association between obe…

The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology…

OBJECTIVE: Sequential therapy in traditional Chinese medicine (TCM) refers to a combination of internal and external treatment methods in a certain order based on syndrome differentiation and therapy. The aim of this study was to evaluate t…

The gut microbiota is a highly complex microbial community residing in the digestive tract of humans and animals, closely linked to host health. Dysbiosis within the gut microbiota has been associated with various diseases. Moreover, it int…

BACKGROUND: Female reproductive disorders (FRDs) are common diseases among women of childbearing age, affecting their reproductive health. Age at first sexual intercourse (AFS) is potentially linked to FRDs, and this study aims to investiga…

BACKGROUND: The composite dietary antioxidant index (CDAI) reflects dietary antioxidant intake. Preliminary studies indicate that higher CDAI levels are associated with a lower prevalence of female infertility. However, the underlying mecha…

OBJECTIVE: To assess the utility of clinical and MRI features in distinguishing ovarian clear cell carcinoma (CCC) from adnexal masses with ovarian-adnexal reporting and data system (O-RADS) MRI scores of 4-5. METHODS: This retrospective s…

BACKGROUND: Endometriosis (EM) is a chronic inflammatory disorder characterized by the growth of ectopic endometrial-like tissue and fibrosis. Metabolic reprogramming, particularly enhanced glycolysis, and immune microenvironment dysregulat…

OBJECTIVE: This study investigates the MRI characteristics of primary and metastatic adult granulosa cell tumor with normal estrogen levels (AGCT-NEL) to enhance clinical understanding and diagnostic accuracy of this disease. METHODS: We c…

BACKGROUND: The occurrence of postoperative depression and anxiety in patients with endometriosis (EMS) not only causes psychological distress, but may also harm their physical health. AIM: To explore the postoperative depression status, a…

PURPOSE: To evaluate the association between Composite Dietary Antioxidant Index (CDAI) and the risk of endometriosis in American women. METHODS: The study adopted a cross-sectional design, incorporating 3862 women aged over 20 years, sele…

Xiaoping Xu, Han Wu, Yang Liu Department of Obstetrics and Gynecology, Deyang People’s Hospital, Deyang, Sichuan, People’s Republic of ChinaCorrespondence: Yang Liu, Department of Obstetrics and Gynecology, Deyang People’s Hospital, 173 Nor…

Infertility is a prevalent problem among 10% of people within their reproductive years. Sometimes, even advanced treatment options like assisted reproduction technology have the potential to result in failed implantation. Because of the exp…

Endometriosis (EMT) -related infertility has been a challenge for clinical research. Many studies have confirmed that abnormal alterations in the immune microenvironment and glycolysis are instrumental in causing EMT-related infertility. Re…

OBJECTIVE: To systematically review and conduct a meta-analysis to assess the effectiveness of dienogest (DNG) in the prolonged conservative drug management of deep infiltrating endometriosis (DIE). The findings from this study are intended…

BACKGROUND: Recent evidence suggests a crucial biological role for Circular RNAs (circRNAs) in keloid diseases, yet the underlying mechanisms remain unclear. This study explored the biological effects and molecular mechanisms of hsa_circ_00…

BACKGROUND: Infertility is a reproductive health problem that attracts worldwide attention. Polycystic ovary syndrome (PCOS) is a major cause of female infertility and patients with obesity and PCOS are particularly common in clinical pract…

Abstract Previous studies have identified associations between immune cell traits and endometriosis, but the causality of these relationships remains uncertain. 731 immune cell signatures associated Single-nucleotide polymorphisms (SNPs) we…

Abstract Background Previous studies have reported an association between gut microbial dysbiosis and ovarian diseases, however, it is not clear whether a causal association exists. Methods Two-sample Mendelian randomization (MR) analysis …

Chlamydia trachomatis, is a kind of obligate intracellular pathogen. The removal of C. trachomatis relies primarily on specific cellular immunity. It is currently considered that CD4+ Th1 cytokine responses are the major protective immunity…

BackgroundSevere acute pancreatitis (SAP) can be fatal if left unrecognized and untreated. The purpose was to develop a machine learning (ML) model for predicting the 30-day all-cause mortality risk in SAP patients and to explain the most i…