Liang Sun

ORCID: 0000-0003-1634-4716 · 10 papers in corpus
lab-animal 2024
Science translational medicine ·doi:10.1126/scitranslmed.adk8230

Endometriosis is a debilitating and painful gynecological inflammatory disease affecting up to 15% of women and transgender men. Current treatments are ineffective for a substantial proportion of patients, underscoring the need for addition…

other 2024
Frontiers in immunology ·doi:10.3389/fimmu.2024.1397633

BACKGROUND: Unexplained recurrent pregnancy loss (URPL) is a clinical dilemma in reproductive fields. Its diagnosis is mainly exclusionary after extensive clinical examination, and some of the patients may still face the risk of miscarriage…

lab-animal 2023
·doi:10.1101/2023.08.28.555101

Abstract Endometriosis is a debilitating and painful gynecological inflammatory disease affecting approximately 15% of women. Current treatments are ineffective for a significant fraction of patients, underscoring the need for new medical t…

other 2019
Nature genetics ·doi:10.1038/s41588-019-0447-2

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

other 2018
Molecular medicine reports ·doi:10.3892/mmr.2018.9346

The aim of the present study was to investigate the effects of Toll‑like receptor (TLR) 9 and CpG oligodeoxynucleotide (CpG‑ODN)1826 on sodium taurocholate‑induced acute pancreatitis (AP) rats at different time points. Pathological examinat…

other 2018
Nature genetics ·doi:10.1038/s41588-017-0011-x

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal gene…

other 2018
Nature genetics ·doi:10.1038/s41588-018-0050-y

In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.

lab-animal 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115620495

Tumor necrosis factor α (TNF-α), a proinflammatory cytokine, may play an important role in the pathogenesis of endometriosis; therefore, TNF-α inhibitors potentially have an effect on endometriosis. To investigate the effect of anti-TNF-α t…

other 2010
Journal of biomedical research ·doi:10.1016/s1674-8301(10)60007-3

OBJECTIVE: Recent studies have shown that the local expression of soluble interleukin (IL) -1 receptor type II (sIL-1 RII) in endometrial tissue of women with endometriosis is decreased, and the depression of IL-1 RII was more significant i…

observational 2009
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals ·doi:10.3109/13547500903183970

Cytokines are key mediators of intercellular communication and are likely to promote the development and progression of endometriosis. Previous studies provided evidence that endometriosis develops as a result of the pathogenetic factors in…