PURPOSE: This study aims to investigate the role of calcitonin gene-related peptide (CGRP) in corneal tissue repair in alkali burn and its underlying neuro-immune mechanisms. METHODS: Mouse corneal nerves were ablated via surgery or resini…
OBJECTIVES: To evaluate the status and methodological quality of randomized controlled trials published in 2024 on Chinese patent medicines and Classic Traditional Chinese Medicine Prescriptions, providing evidence for clinical practice and…
BACKGROUND: Extrauterine adenomyomas (EAs) are rare benign lesions that arise outside the uterus and only rarely involve the lung. CASE PRESENTATION: We describe a 34-year-old woman with a history of multiple gynecological surgeries who wa…
Minhua Zhou,1,* Zhongda Liu,1,* Yiping Ye,2 Xiaojing Liu,1 Yongfei Zheng,2 Tao Sun,1 Xiaofei Xu,3 Chuanxuan Yi,1 Xingzu Ji21Department of Pulmonology, Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Trad…
PURPOSE: Infants born after assisted reproductive technology (ART) have more adverse health outcomes than spontaneously conceived infants. Evidence on the impact of ART on the offspring's visual system, particularly refractive errors (REs),…
BACKGROUND: Keratoconus (KC) is a progressive bilateral corneal ectatic disorder characterized by corneal thinning, irregular astigmatism, and subsequent vision impairment. The main purpose of this study is to investigate sex hormone-mediat…
Precancers, defined as normal-appearing or morphologically altered tissues with a risk of oncogenesis, exhibit various detectable manifestations across anatomical sites, including epithelial dysplasia, metaplasia, hyperplasia, and stromal f…
BACKGROUND: Uterine artery embolization (UAE) is a vital treatment modality for various gynecological conditions. However, complications may arise from the accidental migration of embolic agents into non-target tissues through the uterine a…
Single and multiple endometrial polyps (EP) are common gynecological conditions with differing recurrence rates, influencing clinical treatment decisions. This study aimed to characterize the reproductive tract microbiome in both subtypes t…
Yang Yu,1 Tiantian Sun,2 Jingyu Zhang,2 Songquan Wu,1 Xin Tong,3 Fazheng Zhao,3 Xin Fu1 1School of Medicine, Lishui University, Lishui, 323000, Zhejiang Province, People’s Republic of China; 2School of Pharmacy, Heilongjiang University of C…
Foshou San (FSS), which is a traditional Chinese compound formula. So far, a variety of components have been isolated and identified from its complex composition. These findings endow it with diverse pharmacological activities. According to…
As the fertility risks for older males such as infertility and reduced success rates are on the rise, an increasing number of individuals are turning to Assisted Reproductive Technology (ART) to have offspring. However, the influence of pat…
BACKGROUND: Different endometrial preparation protocols are used prior to frozen-thawed embryo transfer (FET). Optimization of endometrial preparation protocols is mandatory to improve live birth rate and obstetric and perinatal outcomes. I…
Female health and the microbiota of the reproductive tract are closely associated. The research scope on reproductive tract microbiota extends from the vaginal to the upper reproductive tract and from infectious diseases to various benign a…
Metal ions-based regulated cell death (RCD), a form of cell death involving metal ions and controlled by one or more cascade signaling pathways, has recently been termed "metalloptosis". Given the rapid advances in understanding metalloptos…
OBJECTIVE: To investigate the vaginal and gut microbes changes during the carcinogenesis of cervical and the auxiliary diagnostic value. To investigate the effect of microbiome-specific metabolites butyric on cervical cancer cells. METHODS…
PURPOSE: To analyze the level of sex hormone in relation to keratoconus (KC). METHODS: Sixty-two eyes of 62 patients (12 females, 50 males) classified as KC and 120 eyes of 120 patients (21 females, 99 males) with mild to moderate myopia a…
BACKGROUND: Idiopathic hypogonadotropic hypogonadism (IHH) is a rare genetic disease attributed to the disorder of hypothalamic-pituitary-gonadal axis. Mutations in the GNRHR gene are one of the most common genetic causes of IHH. Herein, we…
Objective: To evaluate the efficacy and safety of dienogest (DNG) in the treatment of refractory endometriosis-associated pain (REAP). Methods: In this study, REAP was defined according to the following criteria: (1) the pain duration was ≥…
INTRODUCTION: Recently, the rate of caesarean sections (CS) worldwide has risen and CS-associated complications such as niche have increased substantially. Until now, evidence-based clinical guidelines for the treatment of niche-related sym…
This study aimed to evaluate the clinical characteristics, pregnancy outcomes and prognostic factors for pregnancy of female with chromosomal abnormalities (CAs) after artificial insemination with donor's sperm (AID) treatment.A retrospecti…
We herein present a case of carcinosarcoma arising as a primary lesion in the spleen with the presence of local invasion of chest wall prior to widespread metastasis all over the body of a female aged 64 years. The detailed information of t…