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BACKGROUND: Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity and is associated with pain, infertility, and impaired quality of life. Alth…
INTRODUCTION: Endometriosis is a chronic inflammatory disorder marked by the ectopic growth of endometrial-like tissue, affecting 10–15% of women of reproductive age. Pro-inflammatory cytokines (TNF-α, IL-1β, IL-6) drive inflammation and di…
Abstract Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by ectopic endometrial-like tissue. We investigated gene expression changes in ectopic endometrium from 221 women with histologically confirmed end…
This chapter provides a comprehensive analysis of the genetic factors and environmental influences contributing to endometriosis, highlighting recent advances in genomic research and their implications for personalized medicine approaches. …
Endometriosis disease affects about an estimated number of 176 million women worldwide, which constitutes ~10% of the total female population causing debilitating symptoms of pelvic pain and infertility, thus limiting the quality of reprodu…