Cheuk‐Lun Lee

ORCID: 0000-0003-1553-3478 · 4 papers in corpus
other 2026
Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol-Driven WNT7B Suppression
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202509664

Adult endometrial glands undergo cyclic regeneration and development during the menstrual cycle. Their secretions are vital for endometrial functions and early pregnancy, yet the mechanisms controlling gland development are not well underst…

2025
Single-cell transcriptomics reveals notch regulation in quiescent LEPR⁺ endometrial mesenchymal stem cells.
Stem cell research & therapy ·doi:10.1186/s13287-025-04803-7

BackgroundThe human endometrium is a regenerative tissue relying on stem/progenitor cells. Endometrial mesenchymal stem cells (eMSCs) are typically enriched using perivascular markers like CD140b and CD146. However, the identity of more pri…

2022
Three-dimensional culture models of human endometrium for studying trophoblast-endometrium interaction during implantation.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-022-00973-8

During implantation, a symphony of interaction between the trophoblast originated from the trophectoderm of the implanting blastocyst and the endometrium leads to a successful pregnancy. Defective interaction between the trophoblast and end…

article 2017
Co‐culture with macrophages enhances the clonogenic and invasion activity of endometriotic stromal cells
Cell proliferation ·doi:10.1111/cpr.12330

OBJECTIVE: To study the effect on endometrial and endometriotic cells after co-culture with macrophages, using clonogenic, invasion and self-renewal assays. MATERIALS AND METHODS: Peripheral blood samples, endometrium and endometriotic tiss…