Fan LH

No ORCID on file · 3 papers in corpus · active 2018-2026
2026
The dynamic landscape and conserved regulation of the m6Am and m6A methylomes during the human and mouse oocyte-to-embryo transition.
Nucleic acids research ·doi:10.1093/nar/gkag103

N 6-methyladenosine (m6A) and N6, 2'-O-dimethyladenosine (m6Am) are two RNA modifications that play essential roles in diverse RNA metabolic processes and functions. Despite their importance, the dynamic landscapes and regulatory patterns o…

2020
HIF-1α is a Potential Molecular Target for Herbal Medicine to Treat Diseases.
Drug design, development and therapy ·doi:10.2147/dddt.s274980

HIF-1α is an important factor regulating oxygen balance in mammals, and its expression is closely related to various physiological and pathological conditions of the body. Because HIF-1α plays an important role in the occurrence and develop…

2018
Mitochondrial regulation of [Ca2+]i oscillations during cell cycle resumption of the second meiosis of oocyte.
Cell cycle (Georgetown, Tex.) ·doi:10.1080/15384101.2018.1489179

Oocyte is arrested at metaphase of the second meiosis until fertilization switching on [Ca2+]i oscillations. Oocyte activation inefficiency is the most challenging problem for failed fertilization and embryonic development. Mitochondrial fu…