Sara Kerselaers

No ORCID on file · 2 papers in corpus · active 2022-2023

Study types

  • other 2
other 2023
Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure-Activity Relationship
ACS chemical biology ·doi:10.1021/acschembio.2c00672

TRPM3 is an ion channel that is highly expressed in nociceptive neurons and plays a key role in pain perception. In the presence of the endogenous TRPM3 ligand, pregnenolone sulfate (PS), the antifungal compound clotrimazole (Clt) augments …

other 2022
Loratadine, an antihistaminic drug, suppresses the proliferation of endometrial stromal cells by inhibition of TRPV2
European journal of pharmacology ·doi:10.1016/j.ejphar.2022.175086

The transient receptor potential (TRP) channel TRPV2 is widely expressed in a variety of different cell types and tissues. However, elucidating the exact biological functions of TRPV2 is significantly hampered by the lack of selective pharm…