Patrick Chaltin

No ORCID on file · 3 papers in corpus · active 2020-2026

Study types

  • other 2
other 2026
Stereoselectivity and functional plasticity of a common ligand-binding pocket in TRPM3
Nature communications ·doi:10.1038/s41467-026-71226-0

The transient receptor potential melastatin 3 (TRPM3) channel is a key mediator of peripheral pain signaling, and pathogenic mutations in TRPM3 are linked to neurodevelopmental delay and epilepsy. Despite the therapeutic promise of TRPM3 mo…

other 2022
Loratadine, an antihistaminic drug, suppresses the proliferation of endometrial stromal cells by inhibition of TRPV2
European journal of pharmacology ·doi:10.1016/j.ejphar.2022.175086

The transient receptor potential (TRP) channel TRPV2 is widely expressed in a variety of different cell types and tissues. However, elucidating the exact biological functions of TRPV2 is significantly hampered by the lack of selective pharm…

2020
Small-molecule antibiotic inhibitors of post-translational protein secretion
·doi:10.1101/2020.11.17.387027