Nobuo Yaegashi

ORCID: 0000-0003-2521-039X · 42 papers in corpus
lab-animal 2009
Molecular Endocrinology ·doi:10.1210/mend.23.1.9997

ContextProducts of at least five specific steroidogenic genes, including steroidogenic acute regulatory protein (StAR), which facilitates the initial entry of cytosolic cholesterol into the mitochondrion, side-chain-cleavage enzyme (P450scc…

lab-animal 2008
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2008-1180

CONTEXT: Products of at least five specific steroidogenic genes, including steroidogenic acute regulatory protein (StAR), which facilitates the entry of cytosolic cholesterol into the mitochondrion, side chain cleavage P450 enzyme, 3beta-hy…

lab-animal 2008
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.09.001

OBJECTIVE: To evaluate the effect of photodynamic therapy with aminolevulinic acid (ALA) on human adenomyosis xenografts in a mouse model. DESIGN: Human adenomyosis tissues were implanted SC into nude mice. We measured 5-aminolevulinic aci…

2008
·doi:10.1136/ijgc-00009577-200801000-00035
case-report 2007
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/j.1447-0756.2007.00503.x

Endometriotic nodules in the lower genital tract often cause dysmenorrhea and dyspareunia. We report here a case of posterior vaginal fornix endometriosis that was overlooked for several years. We performed a trans-vaginal resection after t…

case-report 2007
Pathology international ·doi:10.1111/j.1440-1827.2007.02099.x

Malignant ovarian neoplasms derived from ovarian epithelium that produce estrogen are rare among postmenopausal women. Presented herein is a case of stage Ic(a) endometrioid adenocarcinoma in the right ovary of an 81-year-old woman, who com…

lab-animal 2007
Molecular Endocrinology ·doi:10.1210/me.2006-0302

Local estrogen biosynthesis is a major factor in the pathogenesis of endometriosis. Aberrant expression of steroidogenic acute regulatory protein (StAR) and aromatase in endometriotic tissue leads to an up-regulation of estrogen production.…

other 2007
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.08.059

The peak power of uterine peristalses after sacral surface electrical stimulation (ssES) treatment decreased markedly in comparison with that measured before ssES on the day of embryo transfer (ET). This suppression effect of uterine perist…

other 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.01.057

OBJECTIVE: To investigate the effects of a selective cyclooxygenase (COX)-2 inhibitor on endometriosis xenografts in immunodeficient mice. DESIGN: Prospective placebo-controlled study. SETTING: An academic facility at a Japanese universit…

lab-animal 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.066

OBJECTIVE: To evaluate the potential of photodynamic therapy with aminolevulinic acid (ALA) on human adenomyosis-derived cells compared with endometrial stromal cells. DESIGN: In vitro study. SETTING: Department of Obstetrics and Gynecolo…

review 2006
The Tohoku Journal of Experimental Medicine ·doi:10.1620/tjem.210.175

Endometriosis is a condition characterized by ectopic endometrial tissues located outside of the uterus, most commonly found on the pelvic peritoneum or ovary. Endometriosis, which occurs in 7-10% of women in the general population and 71-8…

2005
Journal of Clinical Oncology ·doi:10.1200/jco.2005.23.16_suppl.5050

5050 Background: Epithelial ovarian cancer (EOC) can be subdivided into five major histologic types (Serous(SC), Mucinous(MC), Endometrioid(EC), Clear cell(CC), Undifferentiated (UC)). Among them, CC generally has a poor response to combina…

2003
other 2003
Human Reproduction ·doi:10.1093/humrep/deg007

BACKGROUND: Recent studies have indicated new physiological roles for erythropoietin (Epo) unrelated to erythropoiesis. We previously demonstrated that the Epo concentrations in peritoneal fluid from patients with stage I endometriosis were…

lab-animal 2003
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1034/j.1600-0897.2003.00104.x

PROBLEM: We sought to examine the role of Hsp60, a 60-kDa stress-responsive protein (hsp60) with potent immunostimulatory properties, in the pathophysiology of endometriosis. We investigated the response of peritoneal fluid mononuclear cell…

2002
·doi:10.1016/s0015-0282(01)03061-8
observational 2002
Gynecologic and obstetric investigation ·doi:10.1159/000049421

To estimate the probability of pregnancy in infertile women with endometriosis, two series of multivariate analyses were performed in Tohoku University Hospital. In the first series, from 1993 to 1997, 103 patients participated. The Cox pro…