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Background The Bushen Huoxue formula (BSHX) is a classic traditional Chinese medicine prescription for treating gynecological disorders. However, its specific metabolites and mechanisms against IUA remain to be elucidated. Aim This study ai…
Introduction. Endometriosis affects 10-20% of reproductive-age women. Emerging evidence links the gut microbiota to endometriosis pathogenesis, but observational studies are limited by confounding, reverse causation and uncertainty about wh…
BACKGROUND: Female reproductive diseases-including endometriosis (EMs), uterine fibroids (UFs), polycystic ovary syndrome (PCOS), gestational diabetes mellitus (GDM), eclampsia, ectopic pregnancy (EP), infertility, miscarriage, and ovarian …
Endometriosis (EMS) is a chronic inflammatory disease frequently associated with infertility. N6-methyladenosine (m6A) methylation, the most common form of methylation in eukaryotic mRNAs, has gained attention in the study of female reprodu…
Signal transducer and activator of transcription 3 (STAT3), when phosphorylated at tyrosine 705, plays an important role in endometrial stromal cell decidualization and the receptivity of the endometrial epithelium during embryo implantatio…
Polychlorinated biphenyls (PCBs) contain 209 congeners with various structure-activities. Exposure to PCBs was related to disorders of female reproduction. Endometriosis (EM) is an estrogen- and inflammation-dependent disease with high prev…