Study types
- article 19
- dataset 12
- other 6
- preprint 3
- review 2
Condition tags
- adenomyosis 26
- endometriosis 13
- mesh:D004715 10
- dysmenorrhea 4
- mesh:D004412 2
- infertility 1
- mesh:D017699 1
- irritable_bowel_syndrome 1
- chronic_pelvic_pain 1
Top journals
Frequent coauthors
- Wei SHI 22
- Wang, Xin 15
- Ya-Xin Shi 12
- Zhi-yong Liu 11
- Yanfei Wang 10
- Li Xu 10
- Hong-Yun Liu 9
- Liang, Na 8
- Shi, Yaxin 8
- Sun, Zhonghua 8
Objective: To investigate the clinical efficacy of electrophysiological therapy under different parameter modes in chronic pelvic pain syndrome (CPPS). Methods: A total of 95patients with CPPS from the Department of Urology, First Affiliate…
目的 探讨桂枝-重楼有效成分联用抑制子宫腺肌病(AM)进展的相关分子机制。 方法 利用梯度浓度的重楼皂苷(PP)I、II、VII(PPI、PPII、PPVII)及桂枝有效成分反式肉桂醛(TCA)分别处理子宫腺肌病原代细胞(AMDC),通过CCK-8法检测药物对AMDC活力的影响;正交实验筛选PPII与TCA最佳配比(简称PT),Transwell检测细胞侵袭、迁移能力;网络药理学筛选出PT治疗AM的关键通路;利用梯度浓度的PT腹腔注射ICR小鼠30 d,评价药物的安全性…
OBJECTIVE: To explore factors related to dysmenorrhea in adenomyosis and construct a risk prediction model. METHODS: A cross-sectional survey involving 1636 adenomyosis patients from 37 hospitals nationwide (November 2019-February 2022) wa…
Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the malignant …
OBJECTIVE: This study aimed to explore the differences in symptom clusters of adenomyosis (AM) patients across spatial, temporal, and age-stratified dimensions based on the theory of "Treatment in Accordance with Three Categories of Etiolog…
BACKGROUND: Endometriosis is a common gynecological disease that affects approximately 5 %∼10 % of reproductive-aged women. Zinc (Zn), selenium (Se), copper (Cu), cobalt (Co) and molybdenum (Mo) are essential trace elements and are very imp…
BACKGROUND: The active ingredients of the Chinese medical herb Paris polyphylla, P. polyphylla ethanol extract (PPE) and polyphyllin I (PPI), potentially inhibit epithelial-mesenchymal transition (EMT) in tumors. However, the roles of these…
BACKGROUND: The effect of GuizhiFuling Wan (GFW) on adenomyosis (AM) is definite. This study aimed to explore the mechanism and key therapeutic targets of GFW in treating AM through network pharmacology combined with molecular docking and e…
BACKGROUND: Atypical polypoid adenomyoma (APA) is a rare intrauterine polypoid lesion that occurs predominantly in premenopausal women. Although APA was previously considered a benign lesion and treated conservatively, an increasing number …
Some of the key steps in adenomyosis (AM) are the migration and invasion of adenomyosis derived cells (AMDC); these processes require rearrangement of the cytoskeleton which Rho/ROCK signaling pathway is involved. The aim of the current stu…
Additional file 1: Figure S1. HE staining and QC. (A) Samples from the AM_CTRL, AM_EM and AM_EC groups were HE stained, and the black arrow shows the gland invading the muscular layer. (B) X axis represents the number of UMI in each cell, a…
Additional file 1: Figure S1. HE staining and QC. (A) Samples from the AM_CTRL, AM_EM and AM_EC groups were HE stained, and the black arrow shows the gland invading the muscular layer. (B) X axis represents the number of UMI in each cell, a…
Additional file 2: Table S1. Doublet score and predicted doublets.
Additional file 2: Table S1. Doublet score and predicted doublets.
Additional file 3: Table S2. DEGs of AM_EC vs. AM_EM (all cell types).
Additional file 3: Table S2. DEGs of AM_EC vs. AM_EM (all cell types).
Additional file 4: Table S3. Coexisting genes in Venn.