V. A. Mikhailova — Endo Lab

article 2022

Microvesicles derived from leukocytes in the peripheral blood of patients with external genital endometriosis

·doi:10.15789/1563-0625-mdf-2447

Endometriosis is a chronic gynecological disease, which poses a serious problem in terms of diagnosis and treatment. Despite decades of research, there are no specific signs and symptoms and no blood tests to clinically confirm the diagnosi…

2022

Pro- and Anti-Inflammatory Cytokines in the Context of NK Cell-Trophoblast Interactions.

International journal of molecular sciences ·doi:10.3390/ijms23042387

During pregnancy, uterine NK cells interact with trophoblast cells. In addition to contact interactions, uterine NK cells are influenced by cytokines, which are secreted by the cells of the decidua microenvironment. Cytokines can affect the…

2021

Effects of Microvesicles Derived from NK Cells Stimulated with IL-1β on the Phenotype and Functional Activity of Endothelial Cells.

International journal of molecular sciences ·doi:10.3390/ijms222413663

Microvesicles (MVs) are plasma extracellular vesicles ranging from 100 (150) to 1000 nm in diameter. These are generally produced by different cells through their vital activity and are a source of various protein and non-protein molecules.…

2019

Changes in expression of Ki-67, CD16 and CD56 by natural killer cells from peripheral blood mononuclear cells in the setting of recurrent miscarriage after in vitro culturing in the presence of trophoblast cells and IL-2.

Cytotechnology ·doi:10.1007/s10616-019-00331-4

The aim of this research was to assess the proliferative activity of Natural Killer Cells (NK cells) from Peripheral Blood Mononuclear Cells (PBMCs) in the presence of trophoblast cells in women with a history of recurrent miscarriages. We …