Isabelle Kokorine

No ORCID on file · 7 papers in corpus · active 1995-2004

Study types

  • article 7

Condition tags

  • mesh:D004715 1
article 2004
Focal Expression and Final Activity of Matrix Metalloproteinases May Explain Irregular Dysfunctional Endometrial Bleeding
·doi:10.1016/s0002-9440(10)63277-4
article 2000
The matrix metalloproteinase-1 (MMP-1) expression in the human endometrium is inversely regulated by interleukin-1 alpha and sex steroids.

OBJECTIVE: To investigate the regulation of perimenstrual MMP-1 expression in human endometrium. DESIGN: In vitro study utilizing epithelial-stromal co-cultures. SETTING: Cell Biology Unit, International Institute of Cellular and Molecular …

article 1997
Expression of interstitial collagenase (matrix metalloproteinase-1) is related to the activity of human endometriotic lesions
Fertility and Sterility ·doi:10.1016/s0015-0282(97)81510-5
article 1996
Focal cellular origin and regulation of interstitial collagenase (matrix metalloproteinase-1) are related to menstrual breakdown in the human endometrium
·doi:10.1242/jcs.109.8.2151

Recent studies suggest that interstitial collagenase (MMP-1) is an essential enzyme in the early events leading to menstruation. This study analyses its cellular origin, regulation and relation to extracellular matrix breakdown in the human…

article 1996
Regulation and restricted expression of interstitial collagenase suggest a pivotal role in the initiation of menstruation
·doi:10.1093/humrep/11.suppl_2.134

Collagenases are the only mammalian enzymes able to cleave, at neutral pH, the triple helical domain of fibrillar collagens, major constituents of the extracellular matrix of the endometrium. Interstitial collagenase is expressed, secreted …

article 1995
[Collagenase and Related Matrix Metalloproteinases - a Prominent Role in the Initiation of Menstruation]

The human endometrium shows striking structural changes during the menstrual cycle. If no pregnancy develops, the fall of plasma progesterone and estradiol induces extracellular matrix degradation leading to haemorrhagia and mucosal sheddin…

article 1995
The expression of interstitial collagenase in human endometrium is controlled by progesterone and by oestradiol and is related to menstruation
·doi:10.1042/bj3051027

Human endometrial tissue, sampled at different periods of the reproductive cycle, expressed interstitial collagenase mRNA, protein and activity only just before and during the menstrual period. This clear-cut correlation and the inhibition …