Shujie Yang

ORCID: 0000-0003-1753-3068 · 3 papers in corpus
article 2015
Downregulation of FOXO1 mRNA levels predicts treatment failure in patients with endometrial pathology conservatively managed with progestin-containing intrauterine devices
·doi:10.1016/j.ygyno.2015.10.023

ObjectiveTo examine hormone receptor expression levels and downstream gene activation in pre-treatment and post-treatment biopsies in a cohort of patients with endometrial pathology who were being conservatively managed with a progestin-con…

article 2015
FOXO1 expression could be a predictive marker of endometrial cancer progression in patients treated with progesterone-containing intra uterine device
·doi:10.1016/j.ygyno.2015.07.079
2011
Progesterone: the ultimate endometrial tumor suppressor.
Trends in endocrinology and metabolism: TEM ·doi:10.1016/j.tem.2011.01.005

The uterine endometrium is exquisitely sensitive to steroid hormones that act through well-described nuclear receptors. Estrogen drives epithelial proliferation, and progesterone inhibits growth and causes cell differentiation. The importan…