Yoshiya Ito

No ORCID on file · 9 papers in corpus · active 2019-2025

Study types

  • article 8
  • review 1

Condition tags

  • endometriosis 9
  • mesh:D004715 5
article 2025
Inhibition of VEGFR1 TK Signaling in Peritoneal Macrophages Suppresses Endometriosis Development
In vivo (Athens, Greece) ·doi:10.21873/invivo.14059

Background/Aim: Endometriosis is characterized by the accumulation of immune cells in endometrial lesions and the peritoneal cavity. Macrophages contribute to the growth and neovascularization of endometriotic lesions. Vascular endothelial …

article 2023
Inhibition of TP signaling promotes endometriosis growth and neovascularization
Molecular medicine reports ·doi:10.3892/mmr.2023.13079

Endometriosis is highly dependent on angiogenesis and lymphangiogenesis. Prostaglandin E2, an arachidonic acid metabolite, has been shown to promote the formation of new blood and lymphatic vessels. However, the role of another arachidonic …

review 2022
Biologically active lipids in the regulation of lymphangiogenesis in disease states
Pharmacology & therapeutics ·doi:10.1016/j.pharmthera.2021.108011

Lymphatic vessels have crucial roles in the regulation of interstitial fluids, immune surveillance, and the absorption of dietary fat in the intestine. Lymphatic function is also closely related to the pathogenesis of various disease states…

article 2022
Thromboxane A2 receptor signaling inhibits angiogenesis and lymphangiogenesis in the endometriotic lesions in mice
·doi:10.1254/jpssuppl.96.0_2-b-p-091

Angiogenesis and lymphangiogenesis contribute to the development of endometriosis. We recently reported that thromboxane A2 (TXA2) receptor signaling involves in angiogenesis in critical limb ischemia and lymphangiogenesis in inflamed diaph…

article 2020
Inhibition of receptor activity–modifying protein 1 suppresses the development of endometriosis and the formation of blood and lymphatic vessels
Journal of cellular and molecular medicine ·doi:10.1111/jcmm.15823

Abstract Neuroimmune interactions are involved in the development of endometriosis. Here, we examined the role of a neuropeptide, calcitonin gene–related peptide (CGRP), and its receptor, receptor activity–modifying protein (RAMP) 1, in gro…

article 2020
Lymphangiogenesis induced by vascular endothelial growth factor receptor 1 signaling contributes to the progression of endometriosis in mice
Journal of pharmacological sciences ·doi:10.1016/j.jphs.2020.05.003

Lymphangiogenesis is related to the growth of endometriosis. Here, we examined whether vascular endothelial growth factor (VEGF) receptor 1 (VEGFR1) signaling plays a role in lymphangiogenesis during endometriosis. Endometrial fragments fro…

article 2020
RAMP1 signaling facilitates angiogenesis and lymphangiogenesis in the endometriotic lesions in mice
·doi:10.1254/jpssuppl.93.0_2-yia-59

Newly formation of blood and lymphatic vessels is involved in the development of endometriosis. We have demonstrated that calcitonin gene-related peptide (CGRP) promotes wound healing and wound-associated formation of blood and lymphatic ve…

article 2020
VEGFR1 signaling plays a critical role in endometriosis through increasing lymphangiogenesis
·doi:10.1254/jpssuppl.93.0_2-yia-57

Lymphangiogenesis is associated with the growth of endometriosis. In this study, we examined the role of vascular endothelial growth factor (VEGF) receptor 1 (VEGFR1) signaling in lymphangiogenesis and tissue growth in an endometriosis mode…

article 2019
VEGF Receptor 1-Expressing Macrophages Recruited from Bone Marrow Enhances Angiogenesis in Endometrial Tissues
Scientific reports ·doi:10.1038/s41598-019-43185-8

Abstract Angiogenesis is critical in maintenance of endometrial tissues. Here, we examined the role of VEGF receptor 1 (VEGFR1) signaling in angiogenesis and tissue growth in an endometriosis model. Endometrial fragments were implanted into…