Nobuya Unno

ORCID: 0000-0002-6484-8620 · 13 papers in corpus · active 2010-2021

Study types

  • article 12
  • other 1

Condition tags

  • endometriosis 12
  • mesh:D004716 1
  • endometrioma 1
  • adenomyosis 1
article 2021
Scientific reports ·doi:10.1038/s41598-020-79578-3

In endometriosis, M2 MΦs are dominant in endometriotic lesions, but the actual role of M2 MΦ is unclear. CD206 positive (+) MΦ is classified in one of M2 type MΦs and are known to produce cytokines and chemokines. In the present study, we u…

article 2021
Journal of gynecology obstetrics and human reproduction ·doi:10.1016/j.jogoh.2021.102114

INTRODUCTION: Although various perinatal complications have been reported to be increased in the pregnant patients with adenomyosis, it is not clear what type of patients with adenomyosis is more likely to cause obstetric complications. In …

article 2021
·doi:10.1016/j.jri.2021.103391
article 2021
Biomedicines ·doi:10.3390/biomedicines9111519

Sphingosine 1-phosphate (S1P), an inflammatory mediator, is abundantly contained in red blood cells and platelets. We hypothesized that the S1P concentration in the peritoneal cavity would increase especially during the menstrual phase due …

article 2020
·doi:10.1016/j.jri.2020.103238
other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00090-9

In endometriosis, M2 macrophages (MΦ) are dominant and promote the development of endometriosis lesions. However, the factor(s) which induces M2 MΦ are unknown. In the present study, we focused on interleukin (IL)-33, known as an alarmin an…

article 2020
Journal of cellular and molecular medicine ·doi:10.1111/jcmm.15823

Abstract Neuroimmune interactions are involved in the development of endometriosis. Here, we examined the role of a neuropeptide, calcitonin gene–related peptide (CGRP), and its receptor, receptor activity–modifying protein (RAMP) 1, in gro…

article 2020
Journal of pharmacological sciences ·doi:10.1016/j.jphs.2020.05.003

Lymphangiogenesis is related to the growth of endometriosis. Here, we examined whether vascular endothelial growth factor (VEGF) receptor 1 (VEGFR1) signaling plays a role in lymphangiogenesis during endometriosis. Endometrial fragments fro…

article 2020
Biomedicines ·doi:10.3390/biomedicines8110467

Background: Relaxin (RLX)-2, produced by the corpus luteum and placenta, is known to be potentially effective in fibrotic diseases of the heart, lungs, kidneys, and bladder; however, its effectiveness in endometriosis has not yet been inves…

article 2020
·doi:10.1254/jpssuppl.93.0_2-yia-57

Lymphangiogenesis is associated with the growth of endometriosis. In this study, we examined the role of vascular endothelial growth factor (VEGF) receptor 1 (VEGFR1) signaling in lymphangiogenesis and tissue growth in an endometriosis mode…

article 2019
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.14157

AIM: The aim of this study was to investigate the efficacy of T2 star (T2*) mapping in diagnosing ovarian cysts/ tumors. METHODS: diameter circle, was set as much as possible inside ovarian tumors/cysts to measure T2*values, and mean T2* va…

article 2019
Scientific reports ·doi:10.1038/s41598-019-43185-8

Abstract Angiogenesis is critical in maintenance of endometrial tissues. Here, we examined the role of VEGF receptor 1 (VEGFR1) signaling in angiogenesis and tissue growth in an endometriosis model. Endometrial fragments were implanted into…

article 2010
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2010.12.008