Ashley Dorning

ORCID: 0000-0003-0595-8616 · 2 papers in corpus

article 2021

Bioluminescent imaging in induced mouse models of endometriosis reveals differences in four model variations

Disease models & mechanisms ·doi:10.1242/dmm.049070

Our understanding of the aetiology and pathophysiology of endometriosis remains limited. Disease modelling in the field is problematic as many versions of induced mouse models of endometriosis exist. We integrated bioluminescent imaging of …

article 2019

Macrophage‐derived insulin‐like growth factor‐1 is a key neurotrophic and nerve‐sensitizing factor in pain associated with endometriosis

FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.201900797r

ABSTRACT Endometriosis is a common incurable inflammatory disorder that is associated with debilitating pelvic pain in women. Macrophages are central to the pathophysiology of endometriosis: they dictate the growth and vascularization of en…