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BACKGROUND: The histone modification patterns in endometriosis have not been fully characterized. This gap in knowledge results in a poor understanding of the epigenetic mechanisms (and potential therapeutic targets) at play. We aimed to (1…
This study was conducted to assess genetic associations with endometriosis in a Puerto Rican population. Statistically significant differences in the allelic frequencies and genotype distribution of genetic variants in lysyl oxidase-like pr…
The objective of this study was to assess the burden of endometriosis by obtaining patient-reported outcome data describing the experience of living with this disease. Survey data from 107 women with self-reported, surgically diagnosed endo…
OBJECTIVE: To determine the prevalence of endometriosis and its symptoms in a Puerto Rican cohort, and to describe the menstrual, obstetric, and clinical profiles of the women. METHODS: A self-administered questionnaire was given to 1285 Pu…
Endometriosis is a common, incurable gynecologic disease of unknown etiology, which causes incapacitating pain during menses and infertility. There are no specific non-invasive diagnostic tests for endometriosis, therefore diagnosis is curr…