Sabine Heublein

No ORCID on file · 7 papers in corpus · active 2012-2021

Study types

  • article 5
  • preprint 1
  • review 1

Condition tags

  • endometriosis 6
  • die_deep_infiltrating 1
preprint 2021
Prognostic and Immunological Significance of ARID1A Status in Endometriosis-Associated Ovarian Carcinoma
·doi:10.1101/2021.09.16.21262993

Abstract ARID1A (BAF250a) is a component of the SWI/SNF chromatin modifying complex, plays an important tumor suppressor role, and is considered prognostic in several malignancies. However, in ovarian carcinomas there are contradictory repo…

article 2021
Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8 + TIL infiltration, and provides no independent prognostic value in endometriosis‐associated ovarian carcinomas
The Journal of Pathology ·doi:10.1002/path.5849

Abstract ARID1A (BAF250a) is a component of the SWI/SNF chromatin modifying complex, plays an important tumour suppressor role, and is considered prognostic in several malignancies. However, in ovarian carcinomas there are contradictory rep…

article 2013
Inducers of G-protein coupled estrogen receptor (GPER) in endometriosis: potential implications for macrophages and follicle maturation
Journal of reproductive immunology ·doi:10.1016/j.jri.2012.10.013

Endometriosis is an estrogen dependent chronic inflammation and thus a condition of stress. Though the G-protein coupled estrogen receptor (GPER) has been shown to be up-regulated in ovarian endometriosis, insights involved in inducing this…

review 2013
Macrophages: Are They Involved in Endometriosis, Abortion and Preeclampsia and How?
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi ·doi:10.1272/jnms.80.97

Macrophages hold a key role in both regulating and executing the body's own immune response under various conditions. Hence, although endometriosis, preeclampsia and abortions are clinically different, all three are regarded to involve high…

article 2012
Induction of the G-protein coupled estrogen receptor (GPER) by stress hormones, inflammatory cytokines and estrogen explains its up-regulation in endometriosis
·doi:10.1016/j.jri.2012.03.266
article 2012
Regulation des G-Protein gekoppelten Östrogenrezeptors durch Stress, Entzündung und Östrogen im Rahmen der Pathophysiologie der Ovarendometriose
·doi:10.1055/s-0032-1318542

Endometriose ist durch ektopes endometriales Gewebe, welches unter östrogenvermittelter Wachstumsregulation steht, gekennzeichnet und geht mit reduzierter Fertilität einher. Diese Studie analysierte daher die Expression des G-Protein gekopp…

article 2012
The G-Protein-Coupled Estrogen Receptor (GPER) is Expressed in Normal Human Ovaries and is Upregulated in Ovarian Endometriosis and Pelvic Inflammatory Disease Involving the Ovary
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112446085

Estrogens play a crucial role in maintaining ovarian function. Deregulation of estrogen signals is associated with fertility-impairing disorders. The aim of this study was to investigate whether the G-protein-coupled estrogen receptor (GPER…