Udo Jeschke

PURPOSE: Endometriosis is known to be an underestimated disease. Lately the awareness of the disease seems to have improved. Aim of this analysis is to provide an overview of the development of treatment of patients diagnosed with endometri…

The vitamin D receptor (VDR) and aryl hydrocarbon receptor (AHR) are two nuclear receptors that exert their effects by binding with ligands and forming a molecular complex. These complexes translocate to the nucleus and activate the express…

Among prostaglandins, Prostaglandin E2 (PGE2) (PGE2) is considered especially important for decidualization, ovulation, implantation and pregnancy. Four major PGE2 receptor subtypes, EP1, EP2, EP3, EP4, as well as peroxisome proliferator-ac…

The present study aimed to identify differences in protein expression in cases of endometrioid endometrial cancer (EEC) with and without coexisting adenomyosis uteri (AM), and to evaluate the histopathological and prognostic distinctions. T…

Normal pregnancy is a state of hypercoagulability with diminishing fibrinolytic activity, which is mainly caused by an increase of plasminogen activator inhibitor type 1 (PAI-1). PAI-1 is the main inhibitor of plasminogen activators, includ…

Both the implantation and endometriosis are the results of complicated interaction of sex hormones, prostaglandins and cytokines that designate tissue to adhesion, migration and apoptosis. EP1 and EP3 have been implicated to promote these a…

Background: Implantation and endometriosis are the results of intricate interactions of hormones, prostaglandins and cytokines designating tissues to adhesion, migration and apoptosis. EP1 and EP3 have been implicated in promoting these pro…

Background: VDR and AHR are nuclear receptors, which exert their function through binding with ligands and formation of a molecular complex. These complexes translocate to the nucleus and activate the expression of a series of genes with a …

Endometriosis is considered as a benign aseptic inflammatory disease, characterised by the presence of ectopic endometrium-like tissue. Its symptoms (mostly pain and infertility) are reported as constant stressors. Corticotropin releasing h…

Endometriosis is an inflammatory disease of women of reproductive age featured by the presence of ectopic endometrium and is strongly related to infertility. Galectins, carbonhydrate-binding proteins, have been found to have pro- or anti-in…

Endometriosis is considered as a benign aseptic inflammatory disease, characterised by the presence of ectopic endometrium-like tissue. Its symptoms (mostly pain and infertility) are reported as constant stressors. Corticotropin releasing h…

Macrophages hold a key role in both regulating and executing the body's own immune response under various conditions. Hence, although endometriosis, preeclampsia and abortions are clinically different, all three are regarded to involve high…

Endometriose ist durch ektopes endometriales Gewebe, welches unter östrogenvermittelter Wachstumsregulation steht, gekennzeichnet und geht mit reduzierter Fertilität einher. Diese Studie analysierte daher die Expression des G-Protein gekopp…

Fragestellung: Galektine als kohlenhydratbindende Proteine an der Oberfläche von Zellen spielen bei Zelladhäsionsvorgängen eine wichtige Rolle. Die modulatorische Wirkung der Galektine auf T-Lymphozyten spricht für die Beeinflussung immunol…

Peroxisome proliferator-activated receptors (PPAR) belong to the superfamily of nuclear hormone receptors. Recent investigations emphasize a possible involvement of PPAR in obstetric and gynaecologic disorders like polycystic ovarian syndro…

Endometriosis, a chronic disease characterized by endometrial tissue located outside the uterine cavity, affects one fourth of young women and is associated with chronic pelvic pain and infertility. However, an in-depth understanding of the…