Feifei Fu,1 Feng Lin,2 Xiangjun Yao,1 Zhangbiao Xuan,1 Jialu Gu,1 Dong Shen,1 Shuqin Hu11Department of Gynecology, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang, 312000, People’s Republic of China; 2Department of Urology, A…
PURPOSE: This study aimed to systematically assess the genetic comorbidity of endometriosis (EM) and its subtypes with menstrual-cycle-related traits, and to identify shared genetic mechanisms and key regulatory pathways underlying their as…
Abnormal apoptosis both maintains endometrial cell growth and induces endometrial pathogenesis. The etiology of endometriosis is unclear and no treatment is curative. Therefore, the aim herein was to identify genes involved in the pathogene…
BackgroundThe relationship between dysregulation of the immune system and reproductive health, particularly in the context of abortion, is an area of critical research. Identifying the immunological factors that contribute to abortion could…
Study questionDoes cancer itself, before any gonadotoxic treatment, affect ovarian function in reproductive-aged patients?Summary answerOur study revealed that women with cancer may have decreased ovarian reserve markers even before cancer …
Endometriosis is a common gynecological disease associated with infertility, and it represents an economic burden worldwide. However, the molecular mechanisms underlying endometriosis development have not yet been fully elucidated. Here, we…
BackgroundThe minimum clinically important difference (MCID) was developed to ascertain the smallest change in an outcome that patients perceive as beneficial. The objectives of the present review were (1) to compare the MCIDs for pain asse…
Endometriosis is a complex disease that is influenced by genetic and environmental factors. In endometriosis, WNT4 plays a likely role owing to its biological functions. In this study, the TaqMan allelic discrimination technique was used to…
OBJECTIVE: The purpose of this study is to investigate the potential genetic alterations at DNA level in patients with ovarian endometriosis by high-resolution array-based comparative genomic hybridization (array-CGH) analysis. METHODS: Fol…