Karl Erik Hellstrom

No ORCID on file · 4 papers in corpus
other 2016
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0265

Infertility is a risk factor for ovarian cancer (OvCa). The goal was to determine if antibodies to selenium-binding protein 1 (SBP1), an autoantibody we identified in patients with premature ovarian failure (POF), occurs in both infertility…

other 2013
Gynecologic Oncology ·doi:10.1016/j.ygyno.2013.05.028

OBJECTIVES: To develop an assay for anti-HE4 antibodies and assess such antibodies in sera from women with increased epidemiologic risk for ovarian cancer (infertility) and patients with ovarian cancer in comparison to controls. METHODS: A…

review 2011
Expert opinion on medical diagnostics ·doi:10.1517/17530059.2011.559459

INTRODUCTION: There is a need to improve the diagnosis and prognosis of ovarian carcinoma, particularly the serous type of cancer. Mesothelin and HE4 are two novel biomarkers which are expressed in serous ovarian carcinoma and can be measur…

diagnostic-accuracy 2010
Cancer letters ·doi:10.1016/j.canlet.2010.03.013

The HE4 protein is overexpressed in ovarian carcinomas and can be detected in serum by an ELISA with sensitivity similar to CA125 and higher specificity for malignant disease. We now demonstrate that HE4 can also be detected in the urine at…