Segars J

OBJECTIVE: Up to 1.6% of patients with endometriosis develop epithelial ovarian carcinoma. The genetic overlap between endometriosis and ovarian cancer has not been fully characterized. This review aims to describe the current literature on…

STUDY OBJECTIVE: To develop and validate a non-invasive, blood-based diagnostic assay for endometriosis that performs accurately across menstrual cycle phases and complements existing imaging modalities. DESIGN: Multicenter case-control st…

Endometriosis manifests as ectopic endometrial tissue outside the uterine cavity. This common disease can sometimes appear at unusual anatomical sites or within the intestinal tract, growing as a lesion and mimicking cancer. Such tumor-like…

A systematic review was conducted pertaining to the biologic processes of cumulus cells and measures of oocyte quality. The initial search yielded 18,549 articles, and after screening, 65 studies were included in this review. Extracted data…

OBJECTIVE: To assess the current literature evaluating the epigenetics of endometriosis in humans. EVIDENCE REVIEW: A systematic review was conducted in accordance with the PRISMA guidelines within PubMed, EBSCOhost, Cochrane Library, Emba…

While endometriosis is a common gynecologic disease associated with infertility, the psychosocial impact of endometriosis has not been evaluated against various quality of life (QoL) instruments and compared with other chronic illnesses. We…

PurposeAlthough significant improvements in assisted reproductive technology (ART) outcomes have been accomplished, a critical question remains: which embryo is most likely to result in a pregnancy? Embryo selection is currently based on mo…

Green tea is harvested from the tea plant Camellia sinensis and is one of the most widely consumed beverages worldwide. It is richer in antioxidants than other forms of tea and has a uniquely high content of polyphenolic compounds known as …