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OBJECTIVE: To evaluate the effects of lesion location on adhesion and angiogenesis of transplanted endometriotic lesions in SCID mice. METHODS: Three groups of female SCID mice included intraperitoneal (i.p.) (n = 12), subcutaneous (s.c.) …
OBJECTIVE: To investigate the effects of oxygen on the proliferation and angiogenesis of endometriosis in vivo. DESIGN: Animal studies. SETTING: Animal research facility. ANIMAL(S): Thirty-six female severe combined immunodeficiency (SCI…
OBJECTIVE: To compare the effects of sanjie zhentong capsule (SZC) and danazol on rats with endometriosis (EMT). METHODS: Totally 48 adult female Lewis rats were selected, 12 as the blank control group, and the rest 36 rats in the estrus cy…
Objective To analyze the effect of laparoscopic excision on deep infiltrating type endometriosis(DIE) in posterior pelvis.Methods Data of 35 cases of posterior pelvic DIE admitted to General Hospital of PLA from Jan.2006 to Jan.2009 were re…
BACKGROUND: Direct and indirect evidences have suggested that angiogenesis is a prerequisite for the development of endometriosis. Aiming at offering experimental evidences for anti-angiogenesis therapy, we transplanted the eutopic endometr…
Objective To investigate the effects of antiangiogenesis therapy on the growth and angiogenesis of established endometriosis lesions in the severe combined immunodeficiency disease(SCID)mouse model.Methods Endometrial tissue was obtained fr…
Objective:To investigate the expression of VEGF-C and VEGFR-3 in endometriosis and the relationship between vascular endothelial growth factor and the mechanism of endometriosis. Methods:A total of 32 specimens of endometriosis and 25 speci…
Objective:To investigate the effects of recombinant human endostatin (YH-16) on focus development and angiogenesis of endometriosis (EMS).Methods:Eutopic endometrium from endometriosis was subcutaneously transplanted into SCID mice,and the …
OBJECTIVE: To establish animal models of endometriosis in rhesus monkeys and study the invasion mechanism of endometriosis. METHODS: Five female healthy rhesus monkeys with regular menstrual cycles were selected, of whom 4 were used for end…