Jingfei Chen

No ORCID on file · 4 papers in corpus
other 2025
Development of machine learning models for diagnostic biomarker identification and immune cell infiltration analysis in PCOS
Journal of ovarian research ·doi:10.1186/s13048-024-01583-1

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. It is characterized by symptoms such as hyperandrogenemia, oligo or anovulation and polycystic ovarian, significantly impacting…

lab-animal 2025
Upregulation of PLAU in granulosa cells disrupts steroid hormone synthesis and promotes apoptosis by activating NF-κB signaling pathway in PCOS
Journal of ovarian research ·doi:10.1186/s13048-025-01930-w

BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. Despite its prevalence, the underlying mechanisms contributing to the pathogenesi…

observational 2024
Effects of physical activity on infertility in reproductive females
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-024-01234-6

OBJECTIVES: To explore the relationship between different types of physical activity and female infertility. METHODS: This study analyzed data from 2,796 female participants aged 18-44 years in the United States, obtained from the National…

lab-animal 2019
H19 regulates trophoblastic spheroid adhesion by competitively binding to let-7
Reproduction (Cambridge, England) ·doi:10.1530/rep-18-0339

Integrin β3 (ITGB3), which is the target gene of the miRNA let-7 that can be antagonized by long noncoding RNA (lncRNA) H19, is well known to have a critical role in endometrium receptivity. However, the regulation of ITGB3 in cell-cell or …