Fan T

No ORCID on file · 7 papers in corpus · active 2021-2026

Study types

  • article 1
  • other 1
  • preprint 1

Condition tags

  • endometriosis 3
  • infertility 1
other 2026
Serum metabolic fingerprinting for diagnosis and therapeutic applications of ovarian endometriosis
iScience ·doi:10.1016/j.isci.2026.114887

Ovarian endometriosis (OvE) is a gynecological disorder with endometrial tissue in the ovaries, for which effective non-invasive diagnosis and curative treatments are currently lacking. Serum samples were collected from both discovery and v…

preprint 2025
Interpretable machine-learning-derived diagnostic scoring panel for endometriosis identification: a study of serum amino acid profiling
·doi:10.21203/rs.3.rs-6696073/v1

Abstract Delayed diagnosis of endometriosis (EM) can significantly hinder treatment options and patient prognosis, adversely affecting fertility and increasing the risk of malignancy. Current diagnostic methods are invasive. In our study, …

2025
Neutrophils in cancer: At the crucial crossroads of anti-tumor and pro-tumor.
Cancer communications (London, England) ·doi:10.1002/cac2.70027

Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. Ho…

2024
TGF-β signaling in health, disease, and therapeutics.
Signal transduction and targeted therapy ·doi:10.1038/s41392-024-01764-w

Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every tissue and cell type. The signal transduction of TGF-β can stimulate diverse cellular responses and is particularly critical to embryonic development…

2023
Cortisol dysregulation in anxiety infertile women and the influence on IVF treatment outcome.
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1107765

IntroductionDysregulation of the stress-regulatory hormone cortisol is associated with anxiety, but its potential impact on infertile women and in vitro fertilization (IVF) treatment remains unclear. This prospective cross-sectional study a…

article 2023
Regulation of HAND2 Expression by LncRNA HAND2-AS1 in Ovarian Endometriosis Involving DNA Methylation
Journal of the Endocrine Society ·doi:10.1210/jendso/bvad049

HAND2 is a critical mediator of progesterone receptor signaling in endometrium. Silencing of HAND2 expression is associated with female infertility and endometrial cancers. We recently observed that lncRNA HAND2-AS1 and HAND2 are expressed …

2021
AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes.
Journal of cellular and molecular medicine ·doi:10.1111/jcmm.16375

Previous studies showed that the chemotherapeutic effect of temozolomide (TMZ) and vincristine (VCR) against glioma might be blunted by the co-culture with astrocytes, and connexin-43 (CX43) was thought to play a vital role in the communica…