Yang You

No ORCID on file · 2 papers in corpus · active 2023-2025

Study types

  • article 2

Condition tags

  • endometriosis 1
  • endometrioma 1
article 2025
Iron-responsive ZNF185 overexpression drives mitochondrial fission and endoplasmic reticulum stress via cytoskeletal remodeling in granulosa cells
·doi:10.1038/s41420-025-02719-y

Ovarian endometrioma (OMA), an estrogen-dependent gynecological disorder, is characterized by the presence of abundant free iron resulting from recurrent hemorrhage of endometrial cells within the cyst, which adversely affects ovarian funct…

article 2023
Iron overload modulates follicular microenvironment via ROS/HIF-1α/FSHR signaling
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2022.12.105

Iron is essential for the health of reproductive system, and women with iron overload suffer from ovarian dysfunction and lack effective treatment in fertility preservation. However, the underlying mechanism of the detrimental effects of ir…