International Endometriosis Genetics Consortium

No ORCID on file · 4 papers in corpus · active 2021-2023

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 4
  • irritable_bowel_syndrome 1
  • infertility 1
article 2023
Evidence of shared genetic factors in the etiology of gastrointestinal disorders and endometriosis and clinical implications for disease management
Cell reports. Medicine ·doi:10.1016/j.xcrm.2023.101250

In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed. Using large-scale datasets, we report a genetic correlation between endometriosis and irritable bowel syndrome (IBS), peptic ulcer dise…

article 2023
Genomic characterisation of the overlap of endometriosis with 76 comorbidities identifies pleiotropic and causal mechanisms underlying disease risk
Human genetics ·doi:10.1007/s00439-023-02582-w

Comorbid conditions can be driven by underlying pleiotropic and causal mechanisms that can provide insights into shared molecular and biological processes contributing to disease risk. Endometriosis is a chronic condition affecting one in n…

article 2023
Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosterone
BMC medicine ·doi:10.1186/s12916-023-03184-z

BACKGROUND: Endometriosis affects 1 in 9 women, yet it is poorly understood with long diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the presence of endometrial-like tissue outside of the uterus, its ma…

other 2021
Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus
Human genetics ·doi:10.1007/s00439-021-02312-0

Endometriosis, polycystic ovary syndrome (PCOS) and uterine fibroids have been proposed as endometrial cancer risk factors; however, disentangling their relationships with endometrial cancer is complicated due to shared risk factors and com…