AIM: Curative resection and organ preservation are important to manage rectal gastrointestinal stromal tumors; however, postoperative quality of life, including urinary function, remains a concern. Our prior findings suggest a high incidenc…
The pathophysiology of endometriosis remains incompletely understood, necessitating the development of effective animal models for research. We generated and characterized a luminescent endometriosis mouse model utilizing luminescent B6-CAG…
OBJECTIVES: This study aims to examine the association between migraine and various psychiatric and somatic comorbidities in Japan. DESIGN: Cross-sectional study using existing data of the 2017 Japan National Health and Wellness Survey (NH…
BACKGROUND: Human twin studies and other studies have indicated that chronic pain has heritability that ranges from 30% to 70%. We aimed to identify potential genetic variants that contribute to the susceptibility to chronic pain and effica…
OBJECTIVE: Ovarian cancer has the highest mortality among gynecological cancers. High-grade serous carcinoma (HGSC) is the most common histotype of ovarian cancer regardless of ethnicity, whereas clear cell carcinoma (CCC) is more common in…
BACKGROUND: Mesonephric adenocarcinoma (MA) is a rare tumor believed to arise from mesonephric remnants occurring mostly in the uterine cervix and, to a lesser extent, the corpus. Since the first case report of MA in the corpus in 1995, onl…
We report a case of a clear cell adenocarcinoma arising from a giant cystic adenomyosis, with immunohistochemical analysis of p53 and laminin-5 gamma2 chain overexpression. Microscopically, not only clear cell adenocarcinoma showing myometr…