Richard J. Edmondson

ORCID: 0000-0003-2553-4423 · 4 papers in corpus
other 2023
Journal of medical genetics ·doi:10.1136/jmg-2022-108741

BACKGROUND: Our study aimed to establish 'real-world' performance and cost-effectiveness of ovarian cancer (OC) surveillance in women with pathogenic germline BRCA1/2 variants who defer risk-reducing bilateral salpingo-oophorectomy (RRSO). …

diagnostic-accuracy 2020
BMC cancer ·doi:10.1186/s12885-020-07468-y

BACKGROUND: MCM5 is a protein involved in DNA replication, facilitating cell proliferation. In normal epithelium MCM5 expression is restricted to the cells in the basal proliferative compartments, however in the presence of a tumour MCM5 po…

review 2020
Clinical genetics ·doi:10.1111/cge.13566

Ovarian cancer is the fourth most common cause of cancer-related death in women in the developed world, and one of the most heritable cancers. One of the most significant risk factors for epithelial ovarian cancer (EOC) is a family history …

review 2011
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/igc.0b013e31821d6021

Many gynecological cancers, including epithelial and stromal ovarian cancers; endometrial carcinomas; and some gynecological sarcomas, in particular endometrial stromal sarcomas, express estrogen and/ or progesterone receptors. Hormonal the…