Daniel Escorsim Machado

No ORCID on file · 35 papers in corpus · active 2007-2026

Study types

  • article 19
  • other 9
  • dataset 3
  • review 2
  • meta-analysis 1

Condition tags

  • endometriosis 32
  • infertility 6
  • dyspareunia 5
  • chronic_pelvic_pain 4
  • dysmenorrhea 4
  • die_deep_infiltrating 4
  • endometrioma 2
article 2016
2Programa de Pós-Graduação em Saúde Pública e Meio Ambiente, EscolaCI: 1.21-3.19). No significant differences were found in allA, +405G> C and +936C> T) in endometriosis: a case–control study with Brazilians

Role of vascular endothelial growth factor polymorphisms (−2578C> C, +405G> C and +936C> T polymorphisms between endometriosis cases and controls. A total of six haplotypes Perini et al. BMC Women's Health 2014, 14:117

article 2016
Aberrant levels of Wnt/β-catenin pathway components in a rat model of endometriosis.
Histology and histopathology ·doi:10.14670/hh-11-730

Endometriosis is a benign gynecological disease affecting approximately 10-15% of women of reproductive age and 25-50% of all infertile women. It is characterized by the presence of glands and/or endometrial stroma outside the uterine cavit…

other 2016
Euterpe oleracea Extract (Açaí) Is a Promising Novel Pharmacological Therapeutic Treatment for Experimental Endometriosis
PloS one ·doi:10.1371/journal.pone.0166059

This study investigated the therapeutic potential of Euterpe oleracea extract (açaí) on the growth and survival of endometriotic lesions using an experimental model. Twenty female Sprague-Dawley rats were randomized into two groups after th…

review 2016
Polymorphisms in VEGF and KDR genes in the development of endometriosis: a systematic review
Revista Brasileira de Saúde Materno Infantil ·doi:10.1590/1806-93042016000300002

Abstract Objectives: to review studies that used case-control design to verify the association of polymorphisms in VEGF and KDR genes in the development of endometriosis. Methods: the systematic review selected articles published until Sept…

article 2015
Developing a Noninvasive Procedure Using Labeled Monoclonal Antibody Anti-VEGF (Bevacizumab) for Detection of Endometriosis
BioMed research international ·doi:10.1155/2015/751460

The off-label use of bevacizumab labeled with 99mTc as a new radiopharmaceutical for imaging of endometriosis is a promising noninvasive, new clinical procedure. The bevacizumab in monoclonal antibodies targeted at vascular endothelial grow…

article 2014
A GFP endometriosis model reveals important morphological characteristics of the angiogenic process that govern benign and malignant diseases.
Histology and histopathology ·doi:10.14670/hh-29.903

Endometriosis involves the growth of endometriotic tissue outside the uterine cavity, and is frequently associated with different malignancies. A well-reported alteration in the disease microenvironment is the proliferation of new blood ves…

article 2014
Role of vascular endothelial growth factor polymorphisms (-2578C > A, -460 T > C, -1154G > A, +405G > C and +936C > T) in endometriosis: a case–control study with Brazilians
BMC women's health ·doi:10.1186/1472-6874-14-117

BACKGROUND: Endometriosis is regarded as a complex and heterogeneous disease in which genetic and environmental factors contribute to the phenotype. The Vascular Endothelial Growth Factor (VEGF) plays important roles in the pathogenesis of …

other 2010
A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.11.037

OBJECTIVE: To analyze the antiangiogenic effects of the selective cyclooxygenase-2 (COX-2) inhibitor parecoxib on the growth of endometrial implants in a rat model of peritoneal endometriosis. DESIGN: Pharmacologic interventions in an expe…

article 2010
Higher expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 (Flk-1) and metalloproteinase-9 (MMP-9) in a rat model of peritoneal endometriosis is similar to cancer diseases
Journal of experimental & clinical cancer research : CR ·doi:10.1186/1756-9966-29-4

BACKGROUND: Endometriosis is a common disease characterized by the presence of a functional endometrium outside the uterine cavity, causing pelvic pain, dysmenorrheal, and infertility. This disease has been associated to development of diff…

article 2007
Vascular density and distribution of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 (Flk-1) are significantly higher in patients with deeply infiltrating endometriosis affecting the rectum
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.05.076

ObjectiveTo analyze vascular density and immunolocalization of angiogenic vascular endothelial growth factor (VEGF) and its receptor Flk-1 in the proliferative and secretory eutopic human endometrium and in three different sites of endometr…