Hveem K

No ORCID on file · 4 papers in corpus · active 2015-2024
2024
Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting identifies risk loci associated with appetite, insulin signaling, and brain plasticity
·doi:10.21203/rs.3.rs-5487737/v1

Abstract While most pregnancies are affected by nausea and vomiting, hyperemesis gravidarum (HG) is at the severe end of the clinical spectrum and is associated with dehydration, undernutrition, and adverse maternal, fetal, and child out…

2023
Genetic effects on the timing of parturition and links to fetal birth weight.
Nature genetics ·doi:10.1038/s41588-023-01343-9

The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic basis remains largely unresolved. We present a maternal genome-wide meta-analysis of gestational duration (n = 195,555), identifying 22 associate…

2017
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.
Journal of the American College of Cardiology ·doi:10.1016/j.jacc.2016.11.056

BackgroundGenome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also associated with other diseases or traits.ObjectivesThis st…

2015
New genetic loci link adipose and insulin biology to body fat distribution.
Nature ·doi:10.1038/nature14132

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links…