Yuan Wang

BACKGROUND: To investigate the long-term systemic effects of tubal sterilisation using the silver clip technique, a commonly used yet understudied permanent contraceptive method, by evaluating its impact on inflammatory responses and coagul…

BACKGROUND: Pelvic floor dysfunction (PFD) is a common cause of chronic constipation which can reciprocally exacerbate pelvic floor burden. However, the characteristics and evolution of pelvic floor structures in patients with constipation …

BACKGROUND: The optimal surgical approach for reconstructing abdominal wall defects after radical resection of abdominal wall endometriosis (AWE) remains debated. This study aimed to compare the perioperative safety, recovery outcomes, and …

OBJECTIVE: To describe a mesentery-preserving, nerve-sparing laparoscopic technique for rectal endometriosis. DESIGN: Retrospective cohort study. SETTING: Single centre. POPULATION OR SAMPLE: Women requiring bowel resection for rectal en…

Massive abdominal wall defects resulting from radical abdominal wall endometriosis (AWE) resection present a major reconstructive challenge. This study aims to assess feasibility and short-term safety of a standardized retromuscular-onlay d…

PURPOSE: To investigate the impact of regressed endometrial hyperplasia (EH) on assisted reproductive technology outcomes, particularly in comparison with infertile women with a relatively normal endometrium. METHODS: This retrospective st…

OBJECTIVE: Special attention has been paid to genetic mechanisms that might have a significant impact on the context of the risk of developing endometriosis, in recent years. The study aimed to analyze the expression levels of three inflamm…

BACKGROUND: Visceral fat accumulation and dyslipidaemia are associated with infertility symptoms. The cardiometabolic index (CMI) is a comprehensive quantitative measure of central obesity and dyslipidaemia. However, the link between the fe…

Adenomyosis, characterized by clinical intractability, significantly impacts female fertility and life quality due to the absence of definitive diagnostic markers and effective treatment options. The invagination theory is a primary hypothe…

PURPOSE: This study aimed to develop a joint model combining T2-weighted imaging (T2WI) suppressed fat radiomics, and clinical parameters to predict the energy efficiency factor (EEF) required for high-intensity focused ultrasound (HIFU) ab…

Abdominal wall endometriosis (AWE), often post-cesarean, can cause massive abdominal wall defects following lesion resection. This report details a novel open technique for recurrent massive AWE in a 32-year-old female involving radical exc…

OBJECTIVES: The study aimed to develop a non-enhanced MRI-based radiomics model for the preoperative prediction of the efficacy of adenomyosis after high-intensity focused ultrasound (HIFU) treatment. METHODS: The data of 130 patients with…

Over the years, obesity has become more commonplace and has had a substantial impact on several medical specialties, including reproductive medicine. The potential correlation between the visceral adiposity index (VAI) and infertility has y…

Enhancing the effectiveness of platelet-rich plasma (PRP) for endometrial regeneration is challenging, due to its limited mechanical properties and burst release of growth factors. Here, we proposed an injectable interpenetrating dual-netwo…

CONTEXT: Abnormal endometrial extracellular matrix (ECM) remodeling compromises endometrial receptivity and diminishes the probability of a successful live birth. Serum amyloid A1 (SAA1), a modulator of inflammation, is elevated in the circ…

INTRODUCTION: Many studies have revealed the effect of medical history on dementia. The aim of this study was to explore the relationship between the history of disease and onset of dementia. METHODS: This was a multi-center, cross-section…

The oral microbiome has been implicated in a growing number of diseases; however, determinants of the oral microbiome and their roles remain elusive. Here, we investigated the oral (saliva and tongue dorsum) metagenome, the whole genome, an…

BACKGROUND: Insulin resistance (IR) contributes to ovarian dysfunctions in polycystic ovarian syndrome (PCOS) patients. Serum amyloid A1 (SAA1) is an acute phase protein produced primarily by the liver in response to inflammation. In additi…

Endometriosis (EMS) is a chronic gynecological disease that affects women of childbearing age. However, the exact cause remains unclear. The uterus is a highly vascularized organ that continuously exposes endometrial cells to high oxygen co…

The vagina contains at least a billion microbial cells, dominated by lactobacilli. Here we perform metagenomic shotgun sequencing on cervical and fecal samples from a cohort of 516 Chinese women of reproductive age, as well as cervical, fec…

Although many studies show that patients with diffuse adenomyosis who underwent fertility-sparing surgery can have a successful pregnancy, their pregnancy outcomes are still controversial. The objective of this study was to determine long-t…

Background: Abdominal aggressive fibromatosis (AF) can be confounded with abdominal wall endomentriosis (AWE) because they share considerable similarity. Because of the different patient prognoses and treatment strategies available, accurat…

OBJECTIVE: This study aimed to determine the clinical features of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome patients with functional uterine remnants and endometriosis in a large cohort of Chinese patients. DESIGN: This was a retrospe…