Zhao X

INTRODUCTION: Treatment strategies for endometriosis have traditionally been biomedical. There is a need for a more multidimensional understanding of endometriosis and more targeted and individualized treatment interventions, including psyc…

BackgroundIn assisted reproductive technology (ART) laboratories, semen processing is traditionally performed using manual density gradient centrifugation (DGC), which is labor intensive, time consuming, and subject to inter-technician vari…

ObjectiveTo determine whether blood cadmium levels are associated with the likelihood of developing human papillomavirus infection in women aged 20-59 years.MethodsIn this cross-sectional study, we analyzed data from 7815 women in the 2005-…

Maternal depression and anxiety are common perinatal conditions; however, large-scale, nationally representative evidence on their association with a comprehensive range of obstetric and neonatal outcomes remains limited. The study utilized…

Deep infiltrating endometriosis (DIE) is a severe form of endometriosis that rarely undergoes malignant transformation, and when it does, diagnosis is often difficult. Here, we report two cases of long-standing DIE that progressed to endome…

OBJECTIVE: Adenomyosis is a debilitating gynecologic condition. The present study aimed to compare the effects of laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) on pain relief, menstrual blood loss, and s…

ObjectiveTo evaluate the cost-effectiveness of the levonorgestrel intrauterine system (LNG-IUS) compared with hysteroscopic niche resection (HNR) for women with niche-related postmenstrual spotting.DesignEconomic evaluation from a healthcar…

ObjectiveEnhanced Recovery After Surgery (ERAS) protocols have been proven to optimize recovery in various surgical disciplines, including gynecologic surgery. However, their impact on laparoscopic hysterectomy for benign conditions remains…

Endometriosis (EMs) affects the physical and mental health of a wide range of women of childbearing age. Exploring specific diagnostic targets and screening potential therapeutic drugs will help early diagnosis and improve prognosis. The di…

ObjectivesThis study aims to evaluate the safety and efficacy of ovarian vein embolization combined with polidocanol sclerotherapy for Venous-origin chronic pelvic pain (VO-CPP) and to elucidate potential risk factors affecting prognosis.Me…

BACKGROUND: Direct comparative data on postoperative sexual function between laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) in adenomyosis (AM) remain limited; therefore, this retrospective study compared…

Diminished ovarian reserve (DOR) is associated with poor reproductive outcomes; however, the underlying molecular mechanisms-particularly those involving the regulation of granulosa cell (GC) function by exosomal microRNAs (miRNAs) derived …

Endometriosis is an estrogen-dependent disorder characterized by ectopic growth of endometrial tissue. There is a lack of effective biomarkers for early detection and revealing mechanisms of endometriosis. CSNK2A1 is a compositionally activ…

Aspiration combined with sclerotherapy is widely used for the management of pelvic cystic lesions in patients who are not suitable for surgery. However, the lack of histological confirmation remains a major limitation, particularly in multi…

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder characterized by reproductive and metabolic disturbances, which causes a chronic lack of ovulation that leads to increased incidence of atypical endometrial hyperplasia and …

OBJECTIVES: To evaluate the long-term therapeutic efficacy of laparoscopy combined with transvaginal ultrasound-guided microwave ablation (MWA) for adenomyosis and to identify independent risk factors for postoperative symptomatic recurrenc…

For women with diminished ovarian reserve or of advanced age, controlled ovarian stimulation presents a significant challenge during in vitro fertilization cycles. This multi-center, open-label, randomized controlled trial enrolled 318 wome…

In this study, we identified a number of biological processes, pathways, and key protein targets associated with coenzyme metabolism in bovine clinical mastitis (CM). The expression patterns and subcellular localization of key proteins were…

BACKGROUND: Keratoconus (KC) is a progressive bilateral corneal ectatic disorder characterized by corneal thinning, irregular astigmatism, and subsequent vision impairment. The main purpose of this study is to investigate sex hormone-mediat…

BACKGROUND: The key biomarkers, therapeutic targets, and pathological mechanisms of endometriosis are urgently needed to be elucidated. The role of CTSZ in EM needs to be clarified, and the potential regulatory mechanisms and corresponding …

Intrauterine adhesion arise from aberrant repair and fibrotic remodeling after basal endometrial injury. Hysteroscopic adhesiolysis remains the standard treatment, yet postoperative recurrence stays high and durable preventive strategies re…

BACKGROUND: Intrauterine adhesions (IUA) result from endometrial basal layer injury, leading to fibrous tissue formation and impaired fertility. Current treatments fail to fully reverse the fibrotic microenvironment. This study aimed to elu…

Several diseases affect the female reproductive system, and both disease factors and treatments impact its integrity and function. Consequently, understanding the mechanisms of disease occurrence and exploring treatment methods are key rese…