Jia-Jing Lu

No ORCID on file · 3 papers in corpus
review 2024
Heme metabolism and HO-1 in the pathogenesis and potential intervention of endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13855

Endometriosis (EM) is one of the diseases related to retrograded menstruation and hemoglobin. Heme, released from hemoglobin, is degraded by heme oxygenase-1 (HO-1). In EM lesions, heme metabolites regulate processes such as inflammation, r…

lab-animal 2023
Active Estrogen-Succinate Metabolism Promotes Heme Accumulation and Increases the Proliferative and Invasive Potential of Endometrial Cancer Cells
Biomolecules ·doi:10.3390/biom13071097

Uterine endometrial cancer (UEC) is an estrogen-related tumor. Succinate and heme metabolism play important roles in the progression of multiple tumors. However, the relationship between estrogen, succinate, and heme metabolism and related …

review 2021
Heme oxygenase 1: a novel oncogene in multiple gynecological cancers
International journal of biological sciences ·doi:10.7150/ijbs.61073

Heme oxygenase 1 (HO-1), also known as heat shock protein 32 (HSP32), is a stress-inducible enzyme. In the past, it was believed to participate in maintaining cell homeostasis, reducing oxidative stress damage and exerting anti-apoptotic ef…