Charles Chapron

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Endometriosis is associated with chronic inflammation, and reactive oxygen species (ROS) are proinflammatory mediators that modulate cell proliferation. We have investigated whether the dysregulation of ROS production in endometriotic cells…

ObjectiveTo investigate whether an associated ovarian endometrioma is a marker for severity of deep infiltrating endometriosis (DIE).DesignObservational study between June 1992 and December 2005.SettingUniversity tertiary referral center.Pa…

Journal de Gynecologie Obstetrique et Biologie de la Reproduction - Vol. 32 - N° 8-C2 - p. 32-36

Journal de Gynecologie Obstetrique et Biologie de la Reproduction - Vol. 26 - N° 3 - p. 264

BACKGROUND: Matrix metalloproteinases (MMPs) may contribute to endometriosis. We tested whether eight functional polymorphisms of these genes could modify the risk of endometriosis. METHODS: In this case-control study, 227 endometriosis and…

Endometriosis is a frequent pathology for which the dominant signs and symptoms are pelvic pain and infertility. The physiopathology remains the subject of controversy. Four physiopathological hypotheses have been put forward: regurgitation…

BACKGROUND: Transvaginal ultrasonography (TVUS) has important advantages compared with transrectal ultrasonography (TRUS): it is less invasive, is cost-effective, is a familiar and well-accepted approach, and anesthesia is not required. We …

Endometriosis is a common gynecological disorder characterized by pain and infertility, where the lesions disseminate everywhere in the body with a preference for the pelvis. In that, it could be regarded as a benign metastatic disease, bec…

A 25-year-old woman with unoperated deep endometriosis of the uterosacral ligament suddenly experienced severe abdominal pain, hematuria, hemoperitoneum, and intrauterine death at 31 weeks' gestation. Surgical intervention revealed active h…

OBJECTIVE: It has been hypothesized that bladder endometriotic nodules are an independent form of endometriosis that should be considered a distinct clinical entity. If this is true, the frequency of nonvesical endometriotic lesions in affe…

To the Editor: We read with great interest the article by Agrawal et al. (1) entitled, “Intramedullary Endometriosis of the Conus Medullaris: Case Report.” In particular, we wish to comment on the pathogenesis of intramedullary endometriosi…

ObjectiveTo analyze the lymph node involvement by endometriotic foci in rectosigmoid endometriosis and to correlate it with clinical and histological parameters including the presence of lymphovascular invasions, which could explain this ly…

The diethylstilbestrol (DES) is a synthetic estrogen which was prescribed from 1941 onwards for the prevention of miscarriage. As well as a possible risk of cancer, another side effect of this treatment was the possible abnormality of the g…