Postoperative abdominal/pelvic peritoneal adhesions are a major source of morbidity (bowel obstruction, infertility, ectopic gestation as well as chronic pelvic pain) in women. In this study, we screened various transduction and transcripti…
PURPOSE: Fibroids are the most common smooth muscle overgrowth in women. This study determined the expression and the effect of hypoxia on two potent antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT) on human fibroid cells.…
OBJECTIVE: This study was conducted to determine whether nitric oxide (NO), a potent vasodilator and inhibitor of thrombus formation, is involved in the formation and maintenance of adhesions. METHODS: Skin, subcutaneous tissues, peritoneu…
PROBLEM: Postoperative pelvic adhesions contribute to infertility, pelvic pain, bowel obstruction, and difficult reoperative procedures. METHOD OF STUDY: In the present study, a rat uterine-peritoneal adhesion model was developed to study …
Pelvic adhesions observed in gynecologic patients are a major contributing factor to infertility, pelvic pain, and/or intestinal obstruction. Such adhesions may be the sequelae to inflammatory processes, endometriosis, and prior surgical in…
Laparoscopic surgery as an alternative to traditional laparotomies has become an important modality in the management of gynecologic diseases; however, it is not without potential risks. Case reports describe numerous complications, includi…
Ovarian remnant syndrome occurs infrequently after oophorectomy, yet when present it can contribute greatly to pelvic discomfort. The syndrome may be difficult to diagnose, identify surgically, and treat without intraoperative or postoperat…
Surgical modalities such as electrosurgery and lasers have been used for many years to treat endometriosis. They are relatively unselective with wide scatter, however, leading to the potential for significant tissue damage and injury. As an…
Oophorectomies were performed on 312 women as part of an operative laparoscopic procedure over an eight-year period. The average age of the women was 40.4 +/- 0.6 (SEM) years; 36.5% had previously undergone a hysterectomy. The median operat…
The increasing use of laparoscopy as a therapeutic method mandates a reappraisal of the risks involved. Complications frequently described include injuries to the large and small bowels, bladder, and blood vessels. The world literature repo…
The use of lasers in reproductive pelvic surgery has been established, based more on the reports of clinical experience than demonstration of improved efficacy as compared to other therapeutic modalities. Superiority of one type of laser ov…
Sixty-eight women underwent laparotomy for endometriosis associated with infertility. They were not candidates for laser laparoscopy by our criteria, or they had failed to conceive after previous therapy. The cumulative pregnancy rate was 7…
The major advantage of the argon laser in laparoscopic reproductive pelvic surgery is the ability to transmit the laser beam along a flexible fiber that can easily be directed at a lesion. Its use has been specifically described for the tre…
It has been suggested that the carbon dioxide (CO2) laser, by virtue of its hypothetical capabilities for precise incisions, minimization of tissue handling and bleeding, and shortened operating time, may improve the success rate of gynecol…