João Bosco Pesquero

ORCID: 0000-0002-4507-632X · 2 papers in corpus

lab-animal 2010

Angiostatic activity of human plasminogen fragments is highly dependent on glycosylation

Cancer science ·doi:10.1111/j.1349-7006.2009.01403.x

To assess the importance of carbohydrate moieties to the anti-angiogenic activity of plasminogen fragments, we cloned the fragment corresponding to amino acids Val(79) to Thr(346) (Kint3-4) that presents the three glycosylation sites. The a…

lab-animal 2009

Disrupted cell cycle control in cultured endometrial cells from patients with endometriosis harboring the progesterone receptor polymorphism PROGINS

The American Journal of Pathology ·doi:10.2353/ajpath.2009.080966

Presently, little is understood about how endometriosis is established or maintained, or how genetic factors can predispose women to the disease. Because of the crucial role that the progesterone receptor polymorphism PROGINS plays in predi…