M. Vignali — Endo Lab

article 1997

Laparoscopic management of pelvic pain and adnexal masses in adolescent and paediatric patients

article 1997

O-005 Laparoscopic uterosacral ligament resection for dysmenorrhea associated with endometriosis: Results of a randomized, controlled trial

·doi:10.1016/s0015-0282(97)90638-5

other 1996

Human endometrial stromal cells as a source of soluble intercellular adhesion molecule (ICAM)-1 molecules

Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a019353

Intercellular adhesion molecule (ICAM)-1-mediated cell-cell adhesion is essential for various immunological functions, including natural killer (NK) cell-mediated cytotoxicity against endometrium. The present study was designed to establish…

article 1996

Modulation of NK Cell Lytic Function by Endometrial Secretory Factors: Potential Role in Endometriosis

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1996.tb00179.x

PROBLEM: Development and progression of endometriosis have been suggested to be related to a defect of NK cells in the ability to eliminate endometrial fragments regurgitated with menstrual debris in ectopic sites. However, it has not been …

article 1995

Basic fibroblast growth factor messenger ribonucleic acid levels in eutopic and ectopic human endometrial stromal cells as assessed by competitive polymerase chain reaction amplification

Molecular and cellular endocrinology ·doi:10.1016/0303-7207(95)03687-3

Previous studies have localized basic fibroblast growth factor (bFGF) and its mRNA in normal and neoplastic endometrium but the expression of bGFG mRNA in endometriosis cells is virtually unknown. Our purpose was to investigate the presence…

other 1994

Expression of intercellular adhesion molecule-1 (ICAM-1) on cultured human endometrial stromal cells and its role in the interaction with natural killers

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1994.tb01104.x

PROBLEM: Recent evidence emphasizes the role of natural killer cells (NKs) as potential effectors of peritoneal immune surveillance directed against the outgrowth of endometrial cells, refluxed with menstrual debris, in ectopic sites. This …

article 1994

Gestrinone inhibits macrophage function and mitogen-stimulated lymphocyte proliferation in vitro

Journal of Reproductive Immunology ·doi:10.1016/0165-0378(94)90015-9

Clinical and experimental evidence supports the hypothesis that some steroidal drugs with androgenic effects might influence the immune system. The present study investigated whether gestrinone is able to affect macrophage and lymphocyte ac…

article 1994

Immunosuppressive effect of danazol on lymphocyte-mediated cytotoxicity toward human endometrial stromal cells

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513599409028452

The influence of danazol on the expression of lymphocyte-mediated cytotoxicity toward the stromal component of the endometrium was examined. Stromal cells were isolated from endometrial biopsy specimens of nine women without endometrial pat…

review 1994

The adhesion molecules on human endometrial stromal cells. Immunological implications

Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.1994.tb21734.x

review 1994

The Recurrence of Endometriosis

Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.1994.tb21766.x

letter 1993

“Killer Cells” and Endometriosis

Fertility and sterility ·doi:10.1016/s0015-0282(16)56301-8

article 1992

Danazol Suppresses Both Spontaneous and Activated Human Lymphocyte‐Mediated Cytotoxicity

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1992.tb00754.x

Danazol is an effective drug in the treatment of endometriosis. Previous reports suggest that it can act by influencing the immune system. Thus, in this study we evaluated whether danazol is able to affect the expression of natural and acti…

article 1992

Leuprorelin acetate depot vs danazol in the treatment of endometriosis: results of an open multicentre trial.

Clinical therapeutics

A national multicentre trial was organized in order to compare the efficacy and safety of leuprorelin acetate depot and danazol in the treatment of endometriosis. Sixty-seven patients with pelvic endometriosis of different severity at lapar…

other 1991

Deficient antiendometrium lymphocyte-mediated cytotoxicity in patients with endometriosis

Fertility and sterility ·doi:10.1016/s0015-0282(16)54661-5

OBJECTIVE: To study the possible role of the immune system in the pathogenesis of endometriosis. DESIGN: A cytotoxicity assay by 51Cr release was performed to determine the lymphocyte cytotoxic response toward endometrial targets and an er…