Isabelle M McGrath

No ORCID on file · 10 papers in corpus
other 2025
HGG advances ·doi:10.1016/j.xhgg.2025.100456

Endometriosis is a complex disease, and many genetic and environmental risk factors contribute to disease risk. The genetic risk of endometriosis has been well characterized in genome-wide association studies. While few physiological risk f…

dissertation 2025
·doi:10.14264/a70b1ee
dataset 2023
·doi:10.6084/m9.figshare.24741778.v1

Additional file 1: Table S1. Statin Adjustment Factors and Linear Regression Analysis of Effect of Statin Usage on Biomarker Levels. Table S2. PRS-PheWAS of phecodes in females utilising endometriosis PRS. Table S3. PheWAS of phecodes in fe…

dataset 2023
·doi:10.6084/m9.figshare.24741778

Additional file 1: Table S1. Statin Adjustment Factors and Linear Regression Analysis of Effect of Statin Usage on Biomarker Levels. Table S2. PRS-PheWAS of phecodes in females utilising endometriosis PRS. Table S3. PheWAS of phecodes in fe…

article 2023
Human genetics ·doi:10.1007/s00439-023-02582-w

Comorbid conditions can be driven by underlying pleiotropic and causal mechanisms that can provide insights into shared molecular and biological processes contributing to disease risk. Endometriosis is a chronic condition affecting one in n…

review 2023
Human reproduction update ·doi:10.1093/humupd/dmad009

BACKGROUND: Endometriosis remains a poorly understood disease, despite its high prevalence and debilitating symptoms. The overlap in symptoms and the increased risk of multiple other traits in women with endometriosis is becoming increasing…

other 2023
·doi:10.6084/m9.figshare.c.6965020

Abstract Background Endometriosis affects 1 in 9 women, yet it is poorly understood with long diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the presence of endometrial-like tissue outside of the uterus…

other 2023
·doi:10.6084/m9.figshare.c.6965020.v1

Abstract Background Endometriosis affects 1 in 9 women, yet it is poorly understood with long diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the presence of endometrial-like tissue outside of the uterus…

article 2023
BMC medicine ·doi:10.1186/s12916-023-03184-z

BACKGROUND: Endometriosis affects 1 in 9 women, yet it is poorly understood with long diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the presence of endometrial-like tissue outside of the uterus, its ma…

2021
International journal of molecular sciences ·doi:10.3390/ijms22052556

There is substantial genetic variation for common traits associated with reproductive lifespan and for common diseases influencing female fertility. Progress in high-throughput sequencing and genome-wide association studies (GWAS) have tran…