Lin Chen — Endo Lab

preprint 2025

Single-cell analysis of endometrial proliferation and secretory phases in patients with endometriosis and normal population

·doi:10.21203/rs.3.rs-5954285/v1

Abstract The characteristic of endometriosis is that the endometrial tissue grows in non-endometrial parts such as the pelvis and ovaries, leading to infertility and chronic pain. However, its pathophysiology is still unclear. Using high-p…

review 2023

Research progress of siVEGF complex and their application in antiangiogenic therapy

International journal of pharmaceutics ·doi:10.1016/j.ijpharm.2023.123251

Vascular endothelial growth factor (VEGF) is an important factor in the development of some diseases such as tumors, ocular neovascular disease and endometriosis. Inhibition of abnormal VEGF expression is one of the most effective means of …

article 2018

Decreased Expression of HOXA10 May Activate the Autophagic Process in Ovarian Endometriosis

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118768704

Autophagy is a survival process that maintains homeostasis in all eukaryotic cells. Recent studies show an abnormal autophagic activity in endometriosis, but the role of autophagy is controversial. Homeobox A10 (HOXA10) is a transcription f…