Le Kang

No ORCID on file · 7 papers in corpus · active 2009-2017

Study types

  • article 5
  • other 2

Condition tags

  • adenomyosis 5
  • endometriosis 3
  • dysmenorrhea 1
article 2017
Berberine inhibits the LPS‑induced proliferation and inflammatory response of stromal cells of adenomyosis tissues mediated by the LPS/TLR4 signaling pathway
Experimental and therapeutic medicine ·doi:10.3892/etm.2017.5316

A previous study by our group has demonstrated that lipopolysaccharide (LPS) induces adenomyosis through stimulating inflammatory cell proliferation and invasive growth of stromal cells via Toll-like receptor 4 (TLR4) signaling. The present…

article 2017
Eutopic/ectopic endometrial apoptosis initiated by bilateral uterine artery occlusion: A new therapeutic mechanism for uterus-sparing surgery in adenomyosis
PloS one ·doi:10.1371/journal.pone.0175511

The objective of the present study was to investigate differences in the expression of apoptosis-related factors in the eutopic and ectopic endometrium (EuE/EE) in women with adenomyosis before and after laparoscopic bilateral uterine arter…

article 2016
LPS/TLR4-mediated stromal cells acquire an invasive phenotype and are implicated in the pathogenesis of adenomyosis
Scientific reports ·doi:10.1038/srep21416

The present study tested whether the LPS/TLR4 signal pathway in endometrial stromal cells is essential for the pathogenesis of adenomyosis. We tested the expression of TLR4, MD2 in the endometrium without adenomyosis (CE), the eutopic endom…

article 2015
Clinical analyses of endometriosis after conservative surgery.
International journal of clinical and experimental medicine

OBJECTIVE: To assess the remission rate and outcome of pregnancy of patients who had moderate and severe ovarian endometriosis after conservative surgery. We also wished to analyze the associated factors of recurrence. METHODS: Weconducted …

article 2013
Long-term efficacy and quality of life associated with laparoscopic bilateral uterine artery occlusion plus partial resection of symptomatic adenomyosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2013.11.014
other 2010
Empirical and parametric likelihood interval estimation for populations with many zero values: application for assessing environmental chemical concentrations and reproductive health
Epidemiology (Cambridge, Mass.) ·doi:10.1097/EDE.0b013e3181d7eb68

BACKGROUND: Understanding the health effects associated with environmental chemicals is challenging when individuals have concentrations at or below the laboratory limits of detection as well as when the values may round to zero or are pres…

other 2009
Clinical application and midterm results of laparoscopic partial resection of symptomatic adenomyosis combined with uterine artery occlusion
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2008.12.003

STUDY OBJECTIVE: To examine the clinical application of laparoscopic partial resection of symptomatic adenomyosis combined with uterine artery occlusion (UAO). DESIGN: Retrospective cohort study (Canadian Task Force classification III). S…