Umberto Leone Roberti Maggiore

Pain is the most evident clinical manifestation of deep infiltrating endometriosis (DIE). Several hormonal and immunologic mechanisms are markedly altered in DIE compared with superficial peritoneal and ovarian endometriosis, and may explai…

Endometriosis is an estrogen-dependent inflammatory disease defined by the growth of endometrial stroma and glands outside of the uterus. Epidemiological and clinical studies show that estrogen is essential for the growth of endometriosis. …

OBJECTIVE: To compare the efficacy of two hormonal therapies in treating symptoms caused by bowel endometriosis. DESIGN: Patient preference study. SETTING: University hospital. POPULATION: A total of 143 women with rectovaginal endometri…

INTRODUCTION: Dienogest (DNG) is an oral progestin, derivative of 19-nortestosterone, that has recently been introduced for the treatment of endometriosis. AREAS COVERED: This review examines the clinical efficacy, safety and tolerability …

STUDY QUESTION: Do endometriotic ovarian cysts influence the rate of spontaneous ovulation? SUMMARY ANSWER: Endometriotic cysts, no matter what their volume, do not influence the rate of spontaneous ovulation in the affected ovary. WHAT I…

PURPOSE: To compare the accuracy of multidetector computerized tomography enema (MDCT-e) and magnetic resonance enema (MRI-e) in determining the presence of sigmoid and rectal endometriotic nodules. MATERIALS AND METHODS: 260 women (32.6 ±…

Pelvic pain is a common condition which significantly deteriorates health-related quality of life. The most commonly identified causes of pain in the pelvic region are gynaecologic, urologic, gastrointestinal, neurological, and musculoskele…

OBJECTIVE: To compare the efficacy of norethisterone acetate (NETA; group N) or letrozole combined with NETA (group L) in treating endometriotic ovarian cysts. STUDY DESIGN: This patient-preference study included 20 patients in group N and…

To compare the accuracy of magnetic resonance enema (MR-e) and transvaginal ultrasonography combined with water-contrast in the rectum (RWC-TVS) in diagnosing rectosigmoid endometriotic nodules. This was a prospective cross-sectional study.…

To investigate the changes in the sonographically detectable alterations of the myometrium caused by adenomyosis after treatment with aromatase inhibitor. This prospective study included symptomatic women with adenomyosis. The diagnosis of …

Eleven days after laparoscopic excision of deep endometriosis, a 32-year old patient was admitted to the emergency room of our institution because of severe vaginal bleeding. The patient was apyretic but asthenic; she did not suffer pain sy…

INTRODUCTION: Over the past 30 years, gonadotropin-releasing hormone agonists (GnRH-a) have been used to induce a hypoestrogenic status in women with endometriosis with the aim to cause an improvement in pain symptoms similar to that observ…

Bladder endometriosis causes urinary symptoms including frequency, dysuria, cyclic haematuria and non-urinary pain symptoms. To our knowledge, the association of bladder endometriosis with urinary incontinence has not been described. We pre…

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

OBJECTIVE: To compare the accuracy of multidetector computerized to- mography enteroclysis (MDCT-e) and magnetic resonance enteroclysis (MR-e) in determining the presence and the mucosa layer involvement of sig- moid and rectal endometrioti…