Daniel Bunis

No ORCID on file · 4 papers in corpus · active 2021-2024

Study types

  • preprint 2
  • article 1
  • other 1

Condition tags

  • endometriosis 4
  • infertility 3
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
other 2024
Identifying therapeutic candidates for endometriosis through a transcriptomics-based drug repositioning approach
iScience ·doi:10.1016/j.isci.2024.109388

Existing medical treatments for endometriosis-related pain are often ineffective, underscoring the need for new therapeutic strategies. In this study, we applied a computational drug repurposing pipeline to stratified and unstratified disea…

preprint 2022
Applying a computational transcriptomics-based drug repositioning pipeline to identify therapeutic candidates for endometriosis
·doi:10.1101/2022.12.20.22283736

Abstract Endometriosis is a common, inflammatory pain disorder comprised of disease in the pelvis and abnormal uterine lining and ovarian function that affects ∼200 million women of reproductive age worldwide and up to 50% of those with pel…

article 2022
Whole-Tissue Deconvolution and scRNAseq Analysis Identify Altered Endometrial Cellular Compositions and Functionality Associated With Endometriosis
Frontiers in immunology ·doi:10.3389/fimmu.2021.788315

The uterine lining (endometrium) exhibits a pro-inflammatory phenotype in women with endometriosis, resulting in pain, infertility, and poor pregnancy outcomes. The full complement of cell types contributing to this phenotype has yet to be …

preprint 2021
Whole-tissue deconvolution and scRNAseq analysis identify altered endometrial cellular compositions and functionality associated with endometriosis
·doi:10.1101/2021.08.27.457966

Abstract The uterine lining (endometrium) exhibits a pro-inflammatory phenotype in women with endometriosis, resulting in pain, infertility, and poor pregnancy outcomes. The full complement of cell types contributing to this phenotype has y…